Burn-related chronic neuropathic pain can contribute to a decreased quality of life. When medical and pharmacologic therapies prove ineffective, patients should undergo evaluation for surgical intervention, consisting of a detailed physical examination and elective diagnostic nerve block, to identify an anatomic cause of pain. Based on symptoms and physical examination findings, particularly Tinel's sign, treatments can vary, including a trial of laser therapies, fat grafting, or nerve surgeries (nerve decompression, neuroma excision, targeted muscle reinnervation, regenerative peripheral nerve interfaces, and vascularized denervated muscle targets). It is essential to counsel patients to establish appropriate expectations prior to treatment with a multidisciplinary team.
Keyphrases
- neuropathic pain
- end stage renal disease
- peripheral nerve
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- spinal cord
- stem cells
- spinal cord injury
- mental health
- randomized controlled trial
- adipose tissue
- study protocol
- depressive symptoms
- patients undergoing
- clinical trial
- patient reported outcomes
- fatty acid
- high speed
- tissue engineering