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Effects of fatty acid amide hydrolase inhibitor URB597 in a rat model of trauma-induced long-term anxiety.

Andalib DanandehValentina VozellaJames LimFariba OveisiGina L RamirezDavid MearsGary WynnDaniele Piomelli
Published in: Psychopharmacology (2018)
The results support the hypothesis that anandamide-mediated signaling at CB1 receptors serves an important regulatory function in the stress response, and confirm that FAAH inhibition may offer a potential therapeutic strategy for post-traumatic stress disorder.
Keyphrases
  • fatty acid
  • high glucose
  • diabetic rats
  • transcription factor
  • sleep quality
  • social support
  • oxidative stress
  • trauma patients
  • endothelial cells
  • depressive symptoms