Effects of fatty acid amide hydrolase inhibitor URB597 in a rat model of trauma-induced long-term anxiety.

Andalib DanandehValentina VozellaJames LimFariba OveisiGina L RamirezDavid MearsGary WynnDaniele Piomelli

Published in: Psychopharmacology (2018)

The results support the hypothesis that anandamide-mediated signaling at CB1 receptors serves an important regulatory function in the stress response, and confirm that FAAH inhibition may offer a potential therapeutic strategy for post-traumatic stress disorder.

Keyphrases

fatty acid
high glucose
diabetic rats
transcription factor
sleep quality
social support
oxidative stress
trauma patients
endothelial cells
depressive symptoms