Increased FURIN expression in rheumatoid arthritis patients and its anti-inflammatory effect.
Rong CaoYing ZhangJuping DuShuaishuai ChenNa WangHaijian YingShen BoPublished in: Journal of clinical laboratory analysis (2020)
FURIN levels were significantly increased in the peripheral blood of RA patients and were not associated with disease activity. The inhibition of FURIN in THP-1-derived macrophages with elevated IL-1β levels shows that FURIN may have an anti-inflammatory effect.
Keyphrases
- disease activity
- rheumatoid arthritis patients
- rheumatoid arthritis
- systemic lupus erythematosus
- anti inflammatory
- ankylosing spondylitis
- peripheral blood
- end stage renal disease
- juvenile idiopathic arthritis
- newly diagnosed
- chronic kidney disease
- ejection fraction
- poor prognosis
- peritoneal dialysis
- binding protein
- systemic sclerosis
- interstitial lung disease