Acute Liver Failure Guidelines.
Alexandra ShinginaNizar MukhtarJamilé Wakim-FlemingSaleh AlqahtaniRobert J WongBerkeley N LimketkaiAnne M LarsonLafaine GrantPublished in: The American journal of gastroenterology (2023)
Acute liver failure (ALF) is a rare, acute, potentially reversible condition resulting in severe liver impairment and rapid clinical deterioration in patients without preexisting liver disease. Due to the rarity of this condition, published studies are limited by the use of retrospective or prospective cohorts and lack of randomized controlled trials. Current guidelines represent the suggested approach to the identification, treatment, and management of ALF and represent the official practice recommendations of the American College of Gastroenterology. The scientific evidence was reviewed using the Grading of Recommendations, Assessment, Development and Evaluation process to develop recommendations. When no robust evidence was available, expert opinions were summarized using Key Concepts. Considering the variety of clinical presentations of ALF, individualization of care should be applied in specific clinical scenarios.
Keyphrases
- liver failure
- hepatitis b virus
- clinical practice
- healthcare
- end stage renal disease
- primary care
- quality improvement
- systematic review
- palliative care
- chronic kidney disease
- randomized controlled trial
- drug induced
- intensive care unit
- early onset
- respiratory failure
- cross sectional
- prognostic factors
- pain management
- peritoneal dialysis
- extracorporeal membrane oxygenation
- combination therapy
- bioinformatics analysis