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First-in-human, phase 1 study of PF-06753512, a vaccine-based immunotherapy regimen (VBIR), in non-metastatic hormone-sensitive biochemical recurrence and metastatic castration-resistant prostate cancer (mCRPC).

Karen A AutioCelestia S HiganoLuke NordquistLeonard J ApplemanTian ZhangXin-Hua ZhuHani BabikerNicholas J VogelzangSandip M PrasadMichael T SchweizerRavi A MadanStephane BillotteNora CavazosOrlaith BoggRay LiKam ChanHelen ChoMegan KanedaI-Ming WangJenny ZhengSzu-Yu TangRobert HollingsworthKenneth A KernDaniel P Petrylak
Published in: Journal for immunotherapy of cancer (2023)
NCT02616185.
Keyphrases
  • squamous cell carcinoma
  • small cell lung cancer
  • endothelial cells
  • open label
  • induced pluripotent stem cells
  • pluripotent stem cells
  • randomized controlled trial
  • free survival
  • placebo controlled