The effect of anti-inflammatory treatment on depressive symptoms in spondyloarthritis: does the type of drug matter?

Casper Webers Uta Kiltz Jüergen Braun Désirée Mfm van der Heijde Annelies Boonen

Published in: Rheumatology (Oxford, England) (2022)

Treatment of active SpA also improves depressive symptoms. Especially in axSpA, TNFi have a larger effect than NSAIDs, which is mainly explained by a stronger effect on disease activity. We found no evidence for a direct link between CRP-mediated inflammation and depressive symptoms in SpA.

Keyphrases

depressive symptoms
disease activity
rheumatoid arthritis
systemic lupus erythematosus
social support
ankylosing spondylitis
anti inflammatory
oxidative stress
rheumatoid arthritis patients
sleep quality
emergency department
combination therapy
physical activity
replacement therapy
adverse drug
smoking cessation