Tenecteplase versus Alteplase for Stroke Thrombolysis Evaluation (TASTE): A multicentre, prospective, randomised, open-label, blinded endpoint, controlled phase III non-inferiority trial protocol.
Carlos Garcia EsperonAndrew BivardLeonid ChurilovNeil SprattMichelle RussellBruce C V CampbellPhilip ChoiTimothy KleinigHenry MaHugh Stephen MarkusCarlos MolinaChung Y HsuChon-Haw TsaiAtte MeretojaDaniel StrbianKenneth ButcherTeddy Y WuStephen M DavisGeoffrey Alan DonnanChristopher LeviMark ParsonsPublished in: International journal of stroke : official journal of the International Stroke Society (2023)
This pivotal trial will provide important data on the role of tenecteplase in acute ischemic stroke, and the use of imaging-based treatment decision making for stroke thrombolysis.
Keyphrases
- phase iii
- open label
- study protocol
- clinical trial
- placebo controlled
- double blind
- acute ischemic stroke
- phase ii
- pulmonary embolism
- randomized controlled trial
- atrial fibrillation
- decision making
- phase ii study
- electronic health record
- squamous cell carcinoma
- big data
- cerebral ischemia
- blood brain barrier
- cross sectional
- photodynamic therapy
- subarachnoid hemorrhage