Survival Analysis and Contributing Factors among PCR-Confirmed Adult Inpatients during the Endemic Phase of COVID-19.
Verónica Benites-GodínezMendoza-Cano OliverXochitl TrujilloMónica Riós-SilvaAgustin Lugo-RadilloJaime Alberto Bricio-BarriosHerguin Benjamin Cuevas-ArellanoEder Fernando Ríos-BracamontesWalter Serrano-MorenoRosa Yolitzy Cárdenas-MaríaGreta Mariana Baltazar-RodríguezAna Daniela Ortega-RamírezEfren Murillo-ZamoraPublished in: Diseases (Basel, Switzerland) (2023)
In May 2023, the global health emergency status of COVID-19 concluded, marking the onset of an endemic era. This study assessed survival rates among PCR-confirmed adult inpatients during this phase and determined contributing factors. Employing a survival analysis approach, this investigation utilized a nationwide Mexican cohort encompassing 152 adult inpatients. Survival rates were computed using the Kaplan-Meier method, and a proportional Cox model identified mortality risk factors. Survival rates remained above 65% on day 14 after admission. Vaccination status, including the number of doses administered, was not significantly associated with fatal outcomes. Chronic kidney disease or a history of immunosuppression (due to any cause) increased mortality risk. Our findings underscore the persistent severity of COVID-19 beyond the global health emergency, emphasizing the necessity for tailored interventions for vulnerable patients.
Keyphrases
- global health
- coronavirus disease
- chronic kidney disease
- end stage renal disease
- public health
- sars cov
- risk factors
- emergency department
- free survival
- healthcare
- ejection fraction
- newly diagnosed
- peritoneal dialysis
- cardiovascular disease
- metabolic syndrome
- type diabetes
- respiratory syndrome coronavirus
- cross sectional
- magnetic resonance imaging
- adipose tissue
- smoking cessation
- young adults