Effectiveness and Safety of Oral Anticoagulants in the Treatment of Acute Venous Thromboembolism: A Nationwide Comparative Cohort Study in France.

Laurent BertolettiGaelle GustoArtak KhachatryanNadia QuignotJose ChavesAudrey MoniotRuth Mokgokong

Published in: Thrombosis and haemostasis (2022)

Apixaban was associated with superior safety and effectiveness than VKAs. All-cause mortality was lower in both DOACs than VKAs. Our results support recommendations to use DOACs over VKAs for the treatment of VTE.

Keyphrases

venous thromboembolism
direct oral anticoagulants
atrial fibrillation
oral anticoagulants
systematic review
randomized controlled trial
liver failure
cross sectional
clinical practice
replacement therapy
aortic dissection