Etanercept as a TNF-alpha inhibitor depresses experimental retinal neovascularization.
Yixuan YaoYujuan CaiAiling SuiYiyun YaoTing SuYanji ZhuBing XieXi ShenPublished in: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie (2020)
Etanercept can regulate pro/anti-inflammatory factors and reduce the expression of pro-angiogenic factors by inhibiting NF-κB phosphorylation, thereby reducing RNV formation.
Keyphrases
- anti inflammatory
- rheumatoid arthritis
- signaling pathway
- diabetic retinopathy
- ankylosing spondylitis
- rheumatoid arthritis patients
- juvenile idiopathic arthritis
- poor prognosis
- optical coherence tomography
- disease activity
- vascular endothelial growth factor
- oxidative stress
- lps induced
- pi k akt
- protein kinase
- systemic lupus erythematosus
- binding protein
- long non coding rna
- cell proliferation
- endothelial cells