Comparison of Statin With Ezetimibe Combination Therapy Versus Statin Monotherapy for Primary Prevention in Middle-Aged Adults.
Jung Joon ChaSoon Jun HongSubin LimJu Hyeon KimHyung Joon JooJae Hyoung ParkCheol-Woong YuDo-Sun LimJang-Young KimJin Ok JeongJeong-Hun ShinChi Young ShimJong-Young LeeYoung-Hyo LimChan Joo LeeEun Joo ChoHasung KimJung Kuk LeeKi Chul Sungnull nullPublished in: Korean circulation journal (2024)
Compared to the statin monotherapy, the combination therapy for primary prevention showed no difference in composite outcomes but may reduce mortality risk in relatively healthy middle-aged patients. However, since the study was observational, further randomized clinical trials are needed to confirm these findings.
Keyphrases
- combination therapy
- middle aged
- cardiovascular disease
- coronary artery disease
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- prognostic factors
- open label
- low density lipoprotein
- type diabetes
- randomized controlled trial
- metabolic syndrome
- skeletal muscle
- cross sectional
- weight loss
- study protocol