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A novel simple assay system for the detection of human platelet antigen 15 (HPA-15) alloantibodies based on three techniques: an HPA-15 expressing cell line, a monoclonal antibody-specific antigen-capture method and mixed-passive haemagglutination.

Yangsook KohHiroko NishimiyaHiroko InoueAyaka KishigamiYukari TsujiRumi SakamotoFumiya HirayamaAyumu Kuroishi
Published in: Vox sanguinis (2019)
A novel, easy-to-perform protocol was successfully developed to detect HPA-15 alloantibodies with high specificity and sensitivity.
Keyphrases
  • monoclonal antibody
  • endothelial cells
  • randomized controlled trial
  • pluripotent stem cells
  • structural basis