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Two years with GIOIA 'Effects of gliflozins and gliptins on markers of cardiovascular damage in type 2 diabetes': A prospective, multicentre, quasi-experimental study on sodium-glucose cotransporter 2 and dipeptidyl peptidase-4 inhibitors in diabetes clinical practice.

Miriam LongoPaola CarusoLorenzo ScappaticcioMaria Ida MaiorinoGiuseppe BellastellaAnnalisa CapuanoKatherine EspositoDario Giugliano
Published in: Diabetes, obesity & metabolism (2024)
In a real-world setting, both SGLT-2i and DPP-4i improve glycaemic control persisting after 2 years of treatment, with a robust effect on both CIMT and albuminuria regression for SGLT-2i as compared with DPP-4i in the propensity score matching.
Keyphrases
  • type diabetes
  • clinical practice
  • glycemic control
  • cardiovascular disease
  • insulin resistance
  • oxidative stress
  • study protocol
  • cross sectional
  • randomized controlled trial
  • combination therapy
  • replacement therapy