Postprandial triglyceride-rich lipoproteins promote lipid accumulation and apolipoprotein B-48 receptor transcriptional activity in human circulating and murine bone marrow neutrophils in a fatty acid-dependent manner.

Almudena Ortega-GómezLourdes M VarelaSergio LópezSergio Montserrat de la PazRosario SánchezFrancisco J G MurianaBeatriz BermúdezRocío Abia

Published in: Molecular nutrition & food research (2017)

Postprandial TRLs disrupts the normal biology and function of circulating and BM neutrophils. MUFA- and omega-3 PUFA-rich dietary fats such as virgin olive oil or fish oil has the potential to prevent excessive neutrophil lipid accumulation and activation by targeting the fatty acid composition of TRLs.

Keyphrases

fatty acid
bone marrow
blood glucose
endothelial cells
mesenchymal stem cells
gene expression
induced pluripotent stem cells
transcription factor
weight gain
pluripotent stem cells
risk assessment
human health
heat shock
metabolic syndrome
binding protein
heat stress