Retrospective survival analysis in patients with metastatic pancreatic ductal adenocarcinoma with insulin-treated type 2 diabetes mellitus.

Andrea PrettaPina ZiranuMarco PuzzoniEleonora LaiGiulia OrsiNicole LisciaEleonora MolinaroStefano MarianiLaura RiggiGiulia RovestiMarco DuboisMarco MigliariMara PersanoGiorgio SabaValentino ImperaFrancesca MusioErich BatzellaLaura DemurtasValeria PuscedduGiorgio AstaraLuca FaloppiStefano CascinuKalliopi AndrikouStefano CascinuMario Scartozzi

Published in: Tumori (2020)

Patients with insulin-treated metastatic PDAC showed better OS than non diabetic patients, as demonstrated by both cohorts. The correlation between OS and insulin-treated DM2 should be investigated further through a prospective clinical trial.

Keyphrases

glycemic control
type diabetes
clinical trial
small cell lung cancer
newly diagnosed
cross sectional
randomized controlled trial
insulin resistance
adipose tissue
open label
single molecule