Using real-world data to dynamically predict flares during tapering of biological DMARDs in rheumatoid arthritis: development, validation, and potential impact of prediction-aided decisions.

Matthijs S van der LeeuwMarianne A MesselinkJanneke TekstraOjay MedinaJaap M van LaarSaskia HaitjemaFloris LafeberJosien J Veris-van DierenMarlies C van der GoesAlfons A den BroederPaco M J Welsing

Published in: Arthritis research & therapy (2022)

The clinical impact of the prediction model is currently under investigation in the PATIO randomized controlled trial (Dutch Trial Register number NL9798).

Keyphrases

randomized controlled trial
study protocol
rheumatoid arthritis
clinical trial
electronic health record
disease activity
phase iii
phase ii
big data
rheumatoid arthritis patients
interstitial lung disease
human health
systemic lupus erythematosus
risk assessment
data analysis
idiopathic pulmonary fibrosis