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PERI-operative biologic DMARD management: Stoppage or COntinuation during orthoPaEdic operations (the PERISCOPE trial) - a study protocol for a pragmatic, UK multicentre, superiority randomised controlled trial with an internal pilot, economic evaluation and nested qualitative study.

Samantha GascoyneAndrew MottKatie CarlisleAbhishek AbhishekJoy AdamsonLaura C CoatesBernard van DurenPaul EmerySusan Marion GoodmanCatherine HewittJinshuo LiLaura MandefieldGillian ParkinsonHelena Marzo-OrtegaJames MaxwellJagdeep NanchahalAmar RanganDuncan RichardsSarah RonaldsonSusan ShepherdJohanna TaylorJeremy Mark WilkinsonHemant PanditKulveer Singh Mankia
Published in: BMJ open (2024)
ISRCTN17691638.
Keyphrases
  • study protocol
  • randomized controlled trial
  • clinical trial
  • rheumatoid arthritis
  • open label
  • double blind
  • cross sectional
  • placebo controlled
  • phase ii
  • case control