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Clinical, biological, and outcome features of P2RY8-CRLF2 and CRLF2 over-expression in pediatric B-cell precursor acute lymphoblastic leukemia according to the CCLG-ALL 2008 and 2018 protocol.

Ying WangJun LiTian-Lin XueShuo TianZhi-Xia YueShu-Guang LiuChao Gao
Published in: European journal of haematology (2023)
These findings indicate P2RY8-CRLF2 identifies a subset of patients with specific features and adverse outcomes that could be improved by risk-directed treatment.
Keyphrases
  • acute lymphoblastic leukemia
  • poor prognosis
  • randomized controlled trial
  • genome wide
  • allogeneic hematopoietic stem cell transplantation
  • gene expression
  • dna methylation
  • binding protein
  • combination therapy