DNA Methylation of Birthweight-Blood Pressure Genes and Changes of Blood Pressure in Response to Weight-Loss Diets in the POUNDS Lost Trial.
Minghao KouXiang LiXiaojian ShaoElin GrundbergXuan WangHao MaYoriko HeianzaJosé Alfredo Martínez HernándezGeorge A BrayFrank M SacksLu QiPublished in: Hypertension (Dallas, Tex. : 1979) (2023)
Our findings suggest that DNAm could be a metabolic memory bridging early and later life, and an indicator of more benefits from eating a low-fat weight-loss diet.
Keyphrases
- weight loss
- blood pressure
- bariatric surgery
- dna methylation
- roux en y gastric bypass
- genome wide
- gastric bypass
- hypertensive patients
- heart rate
- clinical trial
- study protocol
- gene expression
- phase iii
- working memory
- adipose tissue
- glycemic control
- randomized controlled trial
- obese patients
- weight gain
- type diabetes
- body mass index
- blood glucose
- fatty acid
- skeletal muscle
- genome wide identification