9- and 13-HODE regulate fatty acid binding protein-4 in human macrophages, but does not involve HODE/GPR132 axis in PPAR-γ regulation of FABP4.

Venkat N VangavetiVenkatesh ShashidharFiona CollierJason HodgeCatherine RushUsman MalabuBernhard BauneRichard Lee Kennedy

Published in: Therapeutic advances in endocrinology and metabolism (2018)

We conclude that GPR132 is an independent monocyte activation marker in diabetes, but does not contribute to PPAR-γ-mediated induction of FABP4 by HODEs.

Keyphrases

fatty acid
binding protein
endothelial cells
type diabetes
cardiovascular disease
dendritic cells
induced pluripotent stem cells
insulin resistance
glycemic control
pluripotent stem cells
peripheral blood
metabolic syndrome
skeletal muscle