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Bone Marrow Avatars: Mimicking Hematopoiesis in a Dish.

Marta DereckaJohn D Crispino
Published in: Cancer discovery (2023)
Faithful recapitulation of human bone marrow complexity has been a major challenge for the sci-entific community for many years. In this issue of Cancer Discovery, Khan and colleagues present an improved induced pluripotent stem cell differentiation protocol that generates bone marrow organoids re-creating key characteristics of human marrow. See related article by Khan et al., p. 364 (8).
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