Carbamazepine, a Histone Deacetylase Inhibitor Induces Apoptosis in Human Colon Adenocarcinoma Cell Line HT-29.
null Sohaib MEzhilarasan DevarajPublished in: Journal of gastrointestinal cancer (2021)
CBZ induced apoptosis in HT-29 cell through ROS generation and caspase 3 expression and these results pave the way for further in vivo studies.
Keyphrases
- induced apoptosis
- histone deacetylase
- endoplasmic reticulum stress
- signaling pathway
- oxidative stress
- endothelial cells
- poor prognosis
- cell death
- single cell
- dna damage
- squamous cell carcinoma
- cell therapy
- induced pluripotent stem cells
- reactive oxygen species
- pluripotent stem cells
- binding protein
- case control
- radiation therapy
- bone marrow
- mesenchymal stem cells