Silver Citrate Nanoparticles Inhibit PMA-Induced TNFα Expression via Deactivation of NF-κB Activity in Human Cancer Cell-Lines, MCF-7.
Ahmed A H AbdellatifZafar RasheedAhmad A AlhowailAbdulmajeed AlqasoumiMansour AlsharidahRiaz A KhanAbdullah S M AljohaniMaha A AldubayanWaleed FaisalPublished in: International journal of nanomedicine (2020)
This is the first report that showed AgNPs-CIT inhibited TNFα expression via deactivation of the NF-κB signaling event in stimulated breast cancer cells. The results have important implications for the development of novel therapeutic strategies for the prevention/treatment of cancers and/or inflammatory disorders.
Keyphrases
- breast cancer cells
- poor prognosis
- signaling pathway
- rheumatoid arthritis
- oxidative stress
- lps induced
- endothelial cells
- pi k akt
- papillary thyroid
- nuclear factor
- silver nanoparticles
- binding protein
- diabetic rats
- long non coding rna
- inflammatory response
- pluripotent stem cells
- young adults
- drug induced
- smoking cessation
- replacement therapy