Methylphenidate Versus Placebo for Treating Fatigue in Patients With Advanced Cancer: Randomized, Double-Blind, Multicenter, Placebo-Controlled Trial.

Patrick Charles StoneOllie MintonAlison Richardson Peter BuckleZinat E EnayatLouise MarstonNick Freemantle

Published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)

After 6 ± 2 weeks of treatment, methylphenidate was not superior to placebo for treating fatigue in advanced cancer. Methylphenidate was safe and well-tolerated.

Keyphrases

double blind
advanced cancer
attention deficit hyperactivity disorder
palliative care
placebo controlled
clinical trial
phase iii
phase ii
sleep quality
autism spectrum disorder
study protocol
randomized controlled trial
physical activity
gestational age
replacement therapy
smoking cessation