Androgen receptor expression inversely correlates with histological grade and N stage in ER+/PgRlow male breast cancer.

Cristian ScatenaRosa ScarpittaLorenzo InnocentiMario MiccoliRachele BiancottiLucrezia DiodatiMatteo GhilliAntonio Giuseppe Naccarato

Published in: Breast cancer research and treatment (2020)

Hormonal factors reveal to play a crucial role in MBC carcinogenesis and progression. Intriguingly, in ER+/PgRlow tumors AR expression significantly correlates with lymph node status, hinting at a favorable biological role of AR in this tumor subgroup.

Keyphrases

lymph node
poor prognosis
estrogen receptor
binding protein
endoplasmic reticulum
neoadjuvant chemotherapy
long non coding rna
single cell
dna methylation
adipose tissue
randomized controlled trial
study protocol
insulin resistance
phase iii
placebo controlled