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Validation of σ 2 R/TMEM97 as a neuropathic pain target: Specificity, human expression and mechanism of action.

Muhammad Saad YousufJames J SahnEric T DavidStephanie ShiersDanielle M RoyerChelsea D GarciaJennifer ZhangVeronica M HongAyesha AhmadBenedict J KolberDaniel J LieblStephen F MartinTheodore John Price
Published in: bioRxiv : the preprint server for biology (2023)
R/TMEM97-targeted therapeutics thus have the potential to offer effective pain relief without the side effects associated with currently available neuropathic pain medicines.
Keyphrases
  • neuropathic pain
  • spinal cord
  • spinal cord injury
  • endothelial cells
  • poor prognosis
  • cancer therapy
  • pluripotent stem cells
  • binding protein
  • chronic pain
  • long non coding rna
  • climate change
  • pain management