Automatic grading of intervertebral disc degeneration in lumbar dog spines.

Frank NiemeyerFabio GalbuseraMartijn BeukersRené JonasYouping TaoMarion Fusellier Marianna A TryfonidouCornelia Neidlinger-WilkeAnnette KienleHans-Joachim Wilke

Published in: JOR spine (2024)

The novel tool was able to accurately and reliably score the severity of disc degeneration in dogs, although with a performance inferior than that of the human model. The tool has potential in the clinical management of disc degeneration in canine patients as well as in longitudinal studies evaluating regenerative therapies in dogs used as animal models of human disorders.

Keyphrases

endothelial cells
end stage renal disease
stem cells
ejection fraction
chronic kidney disease
newly diagnosed
pluripotent stem cells
mesenchymal stem cells
cell therapy
cross sectional
patient reported outcomes