Currently, cervical cancer (CC) is the fourth recorded widespread cancer among women globally. There are still many cases of metastatic or recurring disease discovered, despite the incidence and fatality rates declining due to screening identification and innovative treatment approaches. Palliative chemotherapy continues to be the standard of care for patients who are not contenders for curative therapies like surgery and radiotherapy. This article seeks to provide a thorough and current summary of therapies that have been looked into for the management of CC. The authors emphasize the ongoing trials while reviewing the findings of clinical research. Agents that use biological mechanisms to target different molecular pathways such as epidermal growth factor receptor (EGFR), vascular endothelial growth factor (VEGF), mammalian target of rapamycin (mTOR), poly ADP-ribosepolymerase (PARP), and epigenetic biological mechanisms epitomize and offer intriguing research prospects.
Keyphrases
- epidermal growth factor receptor
- vascular endothelial growth factor
- small cell lung cancer
- tyrosine kinase
- palliative care
- squamous cell carcinoma
- healthcare
- advanced non small cell lung cancer
- locally advanced
- minimally invasive
- endothelial cells
- dna methylation
- clinical trial
- randomized controlled trial
- dna damage
- emergency department
- papillary thyroid
- metabolic syndrome
- polycystic ovary syndrome
- combination therapy
- coronary artery disease
- quality improvement
- oxidative stress
- drug delivery
- dna repair
- rectal cancer
- cancer therapy
- advanced cancer
- phase ii
- young adults
- prognostic factors
- double blind