Intratumoral Transcriptome Heterogeneity Is Associated With Patient Prognosis and Sidedness in Patients With Colorectal Cancer Treated With Anti-EGFR Therapy From the CO.20 Trial.
Elisa FontanaGift NyamundandaDavid CunninghamDongsheng TuMaggie Chon U CheangDerek J JonkerLillian L SiuFrancesco SclafaniKatherine EasonChanthirika RagulanMaria Antonietta BaliSanna Hulkki-WilsonJonathan M LoreePaul M WaringMirella GiordanoPatrick LawrenceDaniel Nava RodriguesRuwaida BegumJeremy D ShapiroTimothy J PriceChiara CremoliniNaureen StarlingFilippo PietrantonioLivio TrusolinoChristopher J O'CallaghanAnguraj SadanandamPublished in: JCO precision oncology (2020)
TA-ness classification is associated with prognosis in patients with mCRC treated with anti-EGFR therapy and may further help understanding the value of sidedness in patients with RAS/BRAF wild-type tumors.