Livio Trusolino

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 38

Top Venues

Nature genetics

Clinical cancer research : an official journal of the American Association for Cancer Research

Cell death & disease

Science translational medicine

Candiolo Cancer Institute - FPO IRCCS

University of Turin (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Candiolo Cancer Institute - FPO IRCCS Dec 01 2017

Italy

Full Professor, University of Torino School of Medicine :: Laboratory of Translational Cancer Medicine

Education History

University of Turin Nov 01 1997

Italy

PHD

Publications

Sudhir B Malla, Ryan M Byrne, Maxime W Lafarge, Shania M Corry, Natalie C Fisher, Petros K Tsantoulis, Megan L Mills, Rachel A Ridgway, Tamsin R M Lannagan, Arafath K Najumudeen, Kathryn L Gilroy, Raheleh Amirkhah, Sarah L Maguire, Eoghan J Mulholland, Hayley L Belnoue-Davis, Elena Grassi, Marco Viviani, Emily Rogan, Keara L Redmond, Svetlana Sakhnevych, Aoife J McCooey, Courtney Bull, Emily Hoey, Nicoleta Sinevici, Holly Hall, Baharak Ahmaderaghi, Enric Domingo, Andrew Blake, Susan D Richman, Claudio Isella, Crispin Miller, Andrea Bertotti, Livio Trusolino, Maurice B Loughrey, Emma M Kerr, Sabine Tejpar, Timothy S Maughan, Mark Lawler, Andrew D Campbell, Simon J Leedham, Viktor Hendrik Koelzer, Owen James Sansom, Philip David Dunne
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer. Nature genetics (2024)
Harshabad Singh, Pranshu Sahgal, Kevin S Kapner, Steven M Corsello, Hersh V Gupta, Rahul Gujrathi, Yvonne Y Li, Andrew D Cherniak, Raquelle El Alam, Joseph A Kerfoot, Elizabeth Andrews, Annette Lee, Chetan Nambiar, Alison M Hannigan, Joshua Remland, Lauren K Brais, Meghan E Leahy, Douglas A Rubinson, Benjamin L Schlechter, Matthew L Meyerson, Yanan Kuang, Cloud P Paweletz, Jessica K Lee, Julia Coelho França Quintanilha, Andrew J Aguirre, Kimberley J Perez, Brandon M Huffman, Humberto Rossi, Thomas A Abrams, Sheheryar K Kabraji, Livio Trusolino, Andrea Bertotti, Ewa T Sicinska, Aparna Raj Parikh, Brian M Wolpin, Alexa B Schrock, Marios Giannakis, Kimmie Ng, Jeffrey A Meyerhardt, Jason L Hornick, Nilay S Sethi, James M Cleary
RAS/RAF co-mutation and ERBB2 copy number modulates HER2 heterogeneity and responsiveness to HER2-directed therapy in colorectal cancer. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Sudhir B Malla, Ryan M Byrne, Maxime W Lafarge, Shania M Corry, Natalie C Fisher, Petros K Tsantoulis, Megan L Mills, Rachel A Ridgway, Tamsin R M Lannagan, Arafath K Najumudeen, Kathryn L Gilroy, Raheleh Amirkhah, Sarah L Maguire, Eoghan J Mulholland, Hayley L Belnoue-Davis, Elena Grassi, Marco Viviani, Emily Rogan, Keara L Redmond, Svetlana Sakhnevych, Aoife J McCooey, Courtney Bull, Emily Hoey, Nicoleta Sinevici, Holly Hall, Baharak Ahmaderaghi, Enric Domingo, Andrew Blake, Susan D Richman, Claudio Isella, Crispin Miller, Andrea Bertotti, Livio Trusolino, Maurice B Loughrey, Emma M Kerr, Sabine Tejpar, null null, Timothy S Maughan, Mark Lawler, Andrew D Campbell, Simon J Leedham, Viktor Hendrik Koelzer, Owen James Sansom, Philip David Dunne
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer. Nature genetics 56 (3) (2024)
Sudhir B Malla, Ryan M Byrne, Maxime W Lafarge, Shania M Corry, Natalie C Fisher, Petros K Tsantoulis, Megan L Mills, Rachel A Ridgway, Tamsin R M Lannagan, Arafath K Najumudeen, Kathryn L Gilroy, Raheleh Amirkhah, Sarah L Maguire, Eoghan J Mulholland, Hayley L Belnoue-Davis, Elena Grassi, Marco Viviani, Emily Rogan, Keara L Redmond, Svetlana Sakhnevych, Aoife J McCooey, Courtney Bull, Emily Hoey, Nicoleta Sinevici, Holly Hall, Baharak Ahmaderaghi, Enric Domingo, Andrew Blake, Susan D Richman, Claudio Isella, Crispin Miller, Andrea Bertotti, Livio Trusolino, Maurice B Loughrey, Emma M Kerr, Sabine Tejpar, Timothy S Maughan, Mark Lawler, Andrew D Campbell, Simon J Leedham, Viktor Hendrik Koelzer, Owen James Sansom, Philip David Dunne
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer. Nature genetics 56 (3) (2024)
Sudhir B Malla, Ryan M Byrne, Maxime W Lafarge, Shania M Corry, Natalie C Fisher, Petros K Tsantoulis, Megan L Mills, Rachel A Ridgway, Tamsin R M Lannagan, Arafath K Najumudeen, Kathryn L Gilroy, Raheleh Amirkhah, Sarah L Maguire, Eoghan J Mulholland, Hayley L Belnoue-Davis, Elena Grassi, Marco Viviani, Emily Rogan, Keara L Redmond, Svetlana Sakhnevych, Aoife J McCooey, Courtney Bull, Emily Hoey, Nicoleta Sinevici, Holly Hall, Baharak Ahmaderaghi, Enric Domingo, Andrew Blake, Susan D Richman, Claudio Isella, Crispin Miller, Andrea Bertotti, Livio Trusolino, Maurice B Loughrey, Emma M Kerr, Sabine Tejpar, null null, Timothy S Maughan, Mark Lawler, Andrew D Campbell, Simon J Leedham, Viktor Hendrik Koelzer, Owen James Sansom, Philip David Dunne
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer. Nature genetics 56 (3) (2024)
Harshabad Singh, Pranshu Sahgal, Kevin S Kapner, Steven M Corsello, Hersh V Gupta, Rahul Gujrathi, Yvonne Y Li, Andrew D Cherniak, Raquelle El Alam, Joseph A Kerfoot, Elizabeth Andrews, Annette Lee, Chetan Nambiar, Alison M Hannigan, Joshua Remland, Lauren K Brais, Meghan E Leahy, Douglas A Rubinson, Benjamin L Schlechter, Matthew L Meyerson, Yanan Kuang, Cloud P Paweletz, Jessica K Lee, Julia Coelho França Quintanilha, Andrew J Aguirre, Kimberley J Perez, Brandon M Huffman, Humberto Rossi, Thomas A Abrams, Sheheryar K Kabraji, Livio Trusolino, Andrea Bertotti, Ewa T Sicinska, Aparna Raj Parikh, Brian M Wolpin, Alexa B Schrock, Marios Giannakis, Kimmie Ng, Jeffrey A Meyerhardt, Jason L Hornick, Nilay S Sethi, James M Cleary
RAS/RAF Comutation and ERBB2 Copy Number Modulates HER2 Heterogeneity and Responsiveness to HER2-directed Therapy in Colorectal Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (8) (2024)
Harshabad Singh, Pranshu Sahgal, Kevin S Kapner, Steven M Corsello, Hersh V Gupta, Rahul Gujrathi, Yvonne Y Li, Andrew D Cherniak, Raquelle El Alam, Joseph A Kerfoot, Elizabeth Andrews, Annette Lee, Chetan Nambiar, Alison M Hannigan, Joshua Remland, Lauren K Brais, Meghan E Leahy, Douglas A Rubinson, Benjamin L Schlechter, Matthew L Meyerson, Yanan Kuang, Cloud P Paweletz, Jessica K Lee, Julia Coelho França Quintanilha, Andrew J Aguirre, Kimberley J Perez, Brandon M Huffman, Humberto Rossi, Thomas A Abrams, Sheheryar K Kabraji, Livio Trusolino, Andrea Bertotti, Ewa T Sicinska, Aparna Raj Parikh, Brian M Wolpin, Alexa B Schrock, Marios Giannakis, Kimmie Ng, Jeffrey A Meyerhardt, Jason L Hornick, Nilay S Sethi, James M Cleary
RAS/RAF Comutation and ERBB2 Copy Number Modulates HER2 Heterogeneity and Responsiveness to HER2-directed Therapy in Colorectal Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (8) (2024)
Sudhir B Malla, Ryan M Byrne, Maxime W Lafarge, Shania M Corry, Natalie C Fisher, Petros K Tsantoulis, Megan L Mills, Rachel A Ridgway, Tamsin R M Lannagan, Arafath K Najumudeen, Kathryn L Gilroy, Raheleh Amirkhah, Sarah L Maguire, Eoghan J Mulholland, Hayley L Belnoue-Davis, Elena Grassi, Marco Viviani, Emily Rogan, Keara L Redmond, Svetlana Sakhnevych, Aoife J McCooey, Courtney Bull, Emily Hoey, Nicoleta Sinevici, Holly Hall, Baharak Ahmaderaghi, Enric Domingo, Andrew Blake, Susan D Richman, Claudio Isella, Crispin Miller, Andrea Bertotti, Livio Trusolino, Maurice B Loughrey, Emma M Kerr, Sabine Tejpar, Timothy S Maughan, Mark Lawler, Andrew D Campbell, Simon J Leedham, Viktor Hendrik Koelzer, Owen James Sansom, Philip David Dunne
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer. Nature genetics 56 (3) (2024)
Harshabad Singh, Pranshu Sahgal, Kevin S Kapner, Steven M Corsello, Hersh V Gupta, Rahul Gujrathi, Yvonne Y Li, Andrew D Cherniak, Raquelle El Alam, Joseph A Kerfoot, Elizabeth Andrews, Annette Lee, Chetan Nambiar, Alison M Hannigan, Joshua Remland, Lauren K Brais, Meghan E Leahy, Douglas A Rubinson, Benjamin L Schlechter, Matthew L Meyerson, Yanan Kuang, Cloud P Paweletz, Jessica K Lee, Julia Coelho França Quintanilha, Andrew J Aguirre, Kimberley J Perez, Brandon M Huffman, Humberto Rossi, Thomas A Abrams, Sheheryar K Kabraji, Livio Trusolino, Andrea Bertotti, Ewa T Sicinska, Aparna Raj Parikh, Brian M Wolpin, Alexa B Schrock, Marios Giannakis, Kimmie Ng, Jeffrey A Meyerhardt, Jason L Hornick, Nilay S Sethi, James M Cleary
RAS/RAF Comutation and ERBB2 Copy Number Modulates HER2 Heterogeneity and Responsiveness to HER2-directed Therapy in Colorectal Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (8) (2024)
Sudhir B Malla, Ryan M Byrne, Maxime W Lafarge, Shania M Corry, Natalie C Fisher, Petros K Tsantoulis, Megan L Mills, Rachel A Ridgway, Tamsin R M Lannagan, Arafath K Najumudeen, Kathryn L Gilroy, Raheleh Amirkhah, Sarah L Maguire, Eoghan J Mulholland, Hayley L Belnoue-Davis, Elena Grassi, Marco Viviani, Emily Rogan, Keara L Redmond, Svetlana Sakhnevych, Aoife J McCooey, Courtney Bull, Emily Hoey, Nicoleta Sinevici, Holly Hall, Baharak Ahmaderaghi, Enric Domingo, Andrew Blake, Susan D Richman, Claudio Isella, Crispin Miller, Andrea Bertotti, Livio Trusolino, Maurice B Loughrey, Emma M Kerr, Sabine Tejpar, Timothy S Maughan, Mark Lawler, Andrew D Campbell, Simon J Leedham, Viktor Hendrik Koelzer, Owen James Sansom, Philip David Dunne
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer. Nature genetics 56 (3) (2024)
Andrea Sartore-Bianchi, Silvia Marsoni, Alessio Amatu, Valter Torri, Emanuela Bonoldi, Alberto Bardelli, Livio Trusolino, Salvatore Siena
How to Test HER2 for Predicting Resistance to Anti-Epidermal Growth Factor Receptor Therapy in Metastatic Colorectal Cancer? Evidence From the Secondary Analysis of Biomarkers of CALGB/SWOG 80405. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2024)
Simonetta Maria Leto, Elena Grassi, Marco Avolio, Valentina Vurchio, Francesca Cottino, Martina Ferri, Eugenia R Zanella, Sofia Borgato, Giorgio Corti, Laura di Blasio, Desiana Somale, Marianela Vara-Messler, Francesco Galimi, Francesco Sassi, Barbara Lupo, Irene Catalano, Marika Pinnelli, Marco Viviani, Luca Sperti, Alfredo Mellano, Alessandro Ferrero, Caterina C Zingaretti, Alberto Puliafito, Luca Primo, Andrea Bertotti, Livio Trusolino
XENTURION is a population-level multidimensional resource of xenografts and tumoroids from metastatic colorectal cancer patients. Nature communications 15 (1) (2024)
Sudhir B Malla, Ryan M Byrne, Maxime W Lafarge, Shania M Corry, Natalie C Fisher, Petros K Tsantoulis, Megan L Mills, Rachel A Ridgway, Tamsin R M Lannagan, Arafath K Najumudeen, Kathryn L Gilroy, Raheleh Amirkhah, Sarah L Maguire, Eoghan J Mulholland, Hayley L Belnoue-Davis, Elena Grassi, Marco Viviani, Emily Rogan, Keara L Redmond, Svetlana Sakhnevych, Aoife J McCooey, Courtney Bull, Emily Hoey, Nicoleta Sinevici, Holly Hall, Baharak Ahmaderaghi, Enric Domingo, Andrew Blake, Susan D Richman, Claudio Isella, Crispin Miller, Andrea Bertotti, Livio Trusolino, Maurice B Loughrey, Emma M Kerr, Sabine Tejpar, Timothy S Maughan, Mark Lawler, Andrew D Campbell, Simon J Leedham, Viktor Hendrik Koelzer, Owen James Sansom, Philip David Dunne
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer. Nature genetics 56 (3) (2024)
Harshabad Singh, Pranshu Sahgal, Kevin S Kapner, Steven M Corsello, Hersh V Gupta, Rahul Gujrathi, Yvonne Y Li, Andrew D Cherniak, Raquelle El Alam, Joseph A Kerfoot, Elizabeth Andrews, Annette Lee, Chetan Nambiar, Alison M Hannigan, Joshua Remland, Lauren K Brais, Meghan E Leahy, Douglas A Rubinson, Benjamin L Schlechter, Matthew L Meyerson, Yanan Kuang, Cloud P Paweletz, Jessica K Lee, Julia Coelho França Quintanilha, Andrew J Aguirre, Kimberley J Perez, Brandon M Huffman, Humberto Rossi, Thomas A Abrams, Sheheryar K Kabraji, Livio Trusolino, Andrea Bertotti, Ewa T Sicinska, Aparna Raj Parikh, Brian M Wolpin, Alexa B Schrock, Marios Giannakis, Kimmie Ng, Jeffrey A Meyerhardt, Jason L Hornick, Nilay S Sethi, James M Cleary
RAS/RAF Comutation and ERBB2 Copy Number Modulates HER2 Heterogeneity and Responsiveness to HER2-directed Therapy in Colorectal Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (8) (2024)
Harshabad Singh, Pranshu Sahgal, Kevin S Kapner, Steven M Corsello, Hersh V Gupta, Rahul Gujrathi, Yvonne Y Li, Andrew D Cherniak, Raquelle El Alam, Joseph A Kerfoot, Elizabeth Andrews, Annette Lee, Chetan Nambiar, Alison M Hannigan, Joshua Remland, Lauren K Brais, Meghan E Leahy, Douglas A Rubinson, Benjamin L Schlechter, Matthew L Meyerson, Yanan Kuang, Cloud P Paweletz, Jessica K Lee, Julia Coelho França Quintanilha, Andrew J Aguirre, Kimberley J Perez, Brandon M Huffman, Humberto Rossi, Thomas A Abrams, Sheheryar K Kabraji, Livio Trusolino, Andrea Bertotti, Ewa T Sicinska, Aparna Raj Parikh, Brian M Wolpin, Alexa B Schrock, Marios Giannakis, Kimmie Ng, Jeffrey A Meyerhardt, Jason L Hornick, Nilay S Sethi, James M Cleary
RAS/RAF Comutation and ERBB2 Copy Number Modulates HER2 Heterogeneity and Responsiveness to HER2-directed Therapy in Colorectal Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (8) (2024)
Sudhir B Malla, Ryan M Byrne, Maxime W Lafarge, Shania M Corry, Natalie C Fisher, Petros K Tsantoulis, Megan L Mills, Rachel A Ridgway, Tamsin R M Lannagan, Arafath K Najumudeen, Kathryn L Gilroy, Raheleh Amirkhah, Sarah L Maguire, Eoghan J Mulholland, Hayley L Belnoue-Davis, Elena Grassi, Marco Viviani, Emily Rogan, Keara L Redmond, Svetlana Sakhnevych, Aoife J McCooey, Courtney Bull, Emily Hoey, Nicoleta Sinevici, Holly Hall, Baharak Ahmaderaghi, Enric Domingo, Andrew Blake, Susan D Richman, Claudio Isella, Crispin Miller, Andrea Bertotti, Livio Trusolino, Maurice B Loughrey, Emma M Kerr, Sabine Tejpar, null null, Timothy S Maughan, Mark Lawler, Andrew D Campbell, Simon J Leedham, Viktor Hendrik Koelzer, Owen James Sansom, Philip David Dunne
Author Correction: Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer. Nature genetics (2024)
Sudhir B Malla, Ryan M Byrne, Maxime W Lafarge, Shania M Corry, Natalie C Fisher, Petros K Tsantoulis, Megan L Mills, Rachel A Ridgway, Tamsin R M Lannagan, Arafath K Najumudeen, Kathryn L Gilroy, Raheleh Amirkhah, Sarah L Maguire, Eoghan J Mulholland, Hayley L Belnoue-Davis, Elena Grassi, Marco Viviani, Emily Rogan, Keara L Redmond, Svetlana Sakhnevych, Aoife J McCooey, Courtney Bull, Emily Hoey, Nicoleta Sinevici, Holly Hall, Baharak Ahmaderaghi, Enric Domingo, Andrew Blake, Susan D Richman, Claudio Isella, Crispin Miller, Andrea Bertotti, Livio Trusolino, Maurice B Loughrey, Emma M Kerr, Sabine Tejpar, null null, Timothy S Maughan, Mark Lawler, Andrew D Campbell, Simon J Leedham, Viktor Hendrik Koelzer, Owen James Sansom, Philip David Dunne
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer. Nature genetics 56 (3) (2024)
Sudhir B Malla, Ryan M Byrne, Maxime W Lafarge, Shania M Corry, Natalie C Fisher, Petros K Tsantoulis, Megan L Mills, Rachel A Ridgway, Tamsin R M Lannagan, Arafath K Najumudeen, Kathryn L Gilroy, Raheleh Amirkhah, Sarah L Maguire, Eoghan J Mulholland, Hayley L Belnoue-Davis, Elena Grassi, Marco Viviani, Emily Rogan, Keara L Redmond, Svetlana Sakhnevych, Aoife J McCooey, Courtney Bull, Emily Hoey, Nicoleta Sinevici, Holly Hall, Baharak Ahmaderaghi, Enric Domingo, Andrew Blake, Susan D Richman, Claudio Isella, Crispin Miller, Andrea Bertotti, Livio Trusolino, Maurice B Loughrey, Emma M Kerr, Sabine Tejpar, Timothy S Maughan, Mark Lawler, Andrew D Campbell, Simon J Leedham, Viktor Hendrik Koelzer, Owen James Sansom, Philip David Dunne
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer. Nature genetics (2024)
Sudhir B Malla, Ryan M Byrne, Maxime W Lafarge, Shania M Corry, Natalie C Fisher, Petros K Tsantoulis, Megan L Mills, Rachel A Ridgway, Tamsin R M Lannagan, Arafath K Najumudeen, Kathryn L Gilroy, Raheleh Amirkhah, Sarah L Maguire, Eoghan J Mulholland, Hayley L Belnoue-Davis, Elena Grassi, Marco Viviani, Emily Rogan, Keara L Redmond, Svetlana Sakhnevych, Aoife J McCooey, Courtney Bull, Emily Hoey, Nicoleta Sinevici, Holly Hall, Baharak Ahmaderaghi, Enric Domingo, Andrew Blake, Susan D Richman, Claudio Isella, Crispin Miller, Andrea Bertotti, Livio Trusolino, Maurice B Loughrey, Emma M Kerr, Sabine Tejpar, Timothy S Maughan, Mark Lawler, Andrew D Campbell, Simon J Leedham, Viktor Hendrik Koelzer, Owen James Sansom, Philip David Dunne
Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer. Nature genetics 56 (3) (2024)
Simonetta Maria Leto, Martina Ferri, Francesco Sassi, Eugenia R Zanella, Francesca Cottino, Valentina Vurchio, Irene Catalano, Alessandro Ferrero, Caterina C Zingaretti, Caterina Marchio, Elena Grassi, Livio Trusolino, Andrea Bertotti
Synthetic Lethal Interaction with BCL-XL Blockade Deepens Response to Cetuximab in Patient-Derived Models of Metastatic Colorectal Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 29 (6) (2023)
Simonetta Maria Leto, Martina Ferri, Francesco Sassi, Eugenia R Zanella, Francesca Cottino, Valentina Vurchio, Irene Catalano, Alessandro Ferrero, Caterina C Zingaretti, Caterina Marchio, Elena Grassi, Livio Trusolino, Andrea Bertotti
Synthetic lethal interaction with BCL-XL blockade deepens response to cetuximab in patient-derived models of metastatic colorectal cancer. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Simonetta Maria Leto, Martina Ferri, Francesco Sassi, Eugenia R Zanella, Francesca Cottino, Valentina Vurchio, Irene Catalano, Alessandro Ferrero, Caterina C Zingaretti, Caterina Marchio, Elena Grassi, Livio Trusolino, Andrea Bertotti
Synthetic Lethal Interaction with BCL-XL Blockade Deepens Response to Cetuximab in Patient-Derived Models of Metastatic Colorectal Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 29 (6) (2023)
Robin Beekhof, Andrea Bertotti, Franziska Böttger, Valentina Vurchio, Francesca Cottino, Eugenia R Zanella, Giorgia Migliardi, Marco Viviani, Elena Grassi, Barbara Lupo, Alexander A Henneman, Jaco C Knol, Thang V Pham, Richard de Goeij-de Haas, Sander R Piersma, Mariette Labots, Henk M W Verheul, Livio Trusolino, Connie R Jiménez
Phosphoproteomics of patient-derived xenographs identifies targets and markers associated with sensitivity and resistance to EGFR blockade in colorectal cancer. Science translational medicine 15 (709) (2023)
Marta Falcinelli, Giulia Dell'Omo, Elena Grassi, Elisa Mariella, Simonetta Maria Leto, Sharon Scardellato, Annalisa Lorenzato, Sabrina Arena, Andrea Bertotti, Livio Trusolino, Alberto Bardelli, Fabrizio d'Adda di Fagagna
Colorectal cancer patient-derived organoids and cell lines harboring ATRX and/or DAXX mutations lack Alternative Lengthening of Telomeres (ALT). Cell death & disease 14 (2) (2023)
Marta Falcinelli, Giulia Dell'Omo, Elena Grassi, Elisa Mariella, Simonetta Maria Leto, Sharon Scardellato, Annalisa Lorenzato, Sabrina Arena, Andrea Bertotti, Livio Trusolino, Alberto Bardelli, Fabrizio d'Adda di Fagagna
Colorectal cancer patient-derived organoids and cell lines harboring ATRX and/or DAXX mutations lack Alternative Lengthening of Telomeres (ALT). Cell death & disease 14 (2) (2023)
Marta Falcinelli, Giulia Dell'Omo, Elena Grassi, Elisa Mariella, Simonetta Maria Leto, Sharon Scardellato, Annalisa Lorenzato, Sabrina Arena, Andrea Bertotti, Livio Trusolino, Alberto Bardelli, Fabrizio d'Adda di Fagagna
Colorectal cancer patient-derived organoids and cell lines harboring ATRX and/or DAXX mutations lack Alternative Lengthening of Telomeres (ALT). Cell death & disease 14 (2) (2023)
Marta Falcinelli, Giulia Dell'Omo, Elena Grassi, Elisa Mariella, Simonetta Maria Leto, Sharon Scardellato, Annalisa Lorenzato, Sabrina Arena, Andrea Bertotti, Livio Trusolino, Alberto Bardelli, Fabrizio d'Adda di Fagagna
Colorectal cancer patient-derived organoids and cell lines harboring ATRX and/or DAXX mutations lack Alternative Lengthening of Telomeres (ALT). Cell death & disease 14 (2) (2023)
Marta Falcinelli, Giulia Dell'Omo, Elena Grassi, Elisa Mariella, Simonetta Maria Leto, Sharon Scardellato, Annalisa Lorenzato, Sabrina Arena, Andrea Bertotti, Livio Trusolino, Alberto Bardelli, Fabrizio d'Adda di Fagagna
Colorectal cancer patient-derived organoids and cell lines harboring ATRX and/or DAXX mutations lack Alternative Lengthening of Telomeres (ALT). Cell death & disease 14 (2) (2023)
Marta Falcinelli, Giulia Dell'Omo, Elena Grassi, Elisa Mariella, Simonetta Maria Leto, Sharon Scardellato, Annalisa Lorenzato, Sabrina Arena, Andrea Bertotti, Livio Trusolino, Alberto Bardelli, Fabrizio d'Adda di Fagagna
Colorectal cancer patient-derived organoids and cell lines harboring ATRX and/or DAXX mutations lack Alternative Lengthening of Telomeres (ALT). Cell death & disease 14 (2) (2023)
Eugenia R Zanella, Elena Grassi, Livio Trusolino
Towards precision oncology with patient-derived xenografts. Nature reviews. Clinical oncology 19 (11) (2022)
Patricia Jaaks, Elizabeth A Coker, Daniel J Vis, Olivia Edwards, Emma F Carpenter, Simonetta Maria Leto, Lisa Dwane, Francesco Sassi, Howard Lightfoot, Syd Barthorpe, Dieudonne van der Meer, Wanjuan Yang, Alexandra Beck, Tatiana Mironenko, Caitlin Hall, James A Hall, Iman Mali, Laura Richardson, Charlotte Tolley, James Morris, Frances Thomas, Ermira Lleshi, Nanne Aben, Cyril H Benes, Andrea Bertotti, Livio Trusolino, Lodewyk F A Wessels, Mathew J Garnett
Effective drug combinations in breast, colon and pancreatic cancer cells. Nature 603 (7899) (2022)
Martina Tedesco, Francesca Giannese, Dejan Lazarević, Valentina Giansanti, Dalia Rosano, Silvia Monzani, Irene Catalano, Elena Grassi, Eugenia R Zanella, Oronza A Botrugno, Leonardo Morelli, Paola Panina Bordignon, Giulio Caravagna, Andrea Bertotti, Gianvito Martino, Luca Aldrighetti, Sebastiano Pasqualato, Livio Trusolino, Davide Cittaro, Giovanni Tonon
Chromatin Velocity reveals epigenetic dynamics by single-cell profiling of heterochromatin and euchromatin. Nature biotechnology (2021)
Xing Yi Woo, Jessica Giordano, Anuj Srivastava, Zi-Ming Zhao, Michael W Lloyd, Roebi de Bruijn, Yun-Suhk Suh, Rajesh Patidar, Li Chen, Sandra Scherer, Matthew H Bailey, Chieh-Hsiang Yang, Emilio Cortes-Sanchez, Yuanxin Xi, Jing Wang, Jayamanna Wickramasinghe, Andrew V Kossenkov, Vito W Rebecca, Hua Sun, R Jay Mashl, Sherri R Davies, Ryan Jeon, Christian Frech, Jelena Randjelovic, Jacqueline Rosains, Francesco Galimi, Andrea Bertotti, Adam Lafferty, Alice C O'Farrell, Elodie Modave, Diether Lambrechts, Petra Ter Brugge, Violeta Serra, Elisabetta Marangoni, Rania El Botty, Hyunsoo Kim, Jong-Il Kim, Han-Kwang Yang, Charles Lee, Dennis A Dean, Brandi Davis-Dusenbery, Yvonne A Evrard, James H Doroshow, Alana L Welm, Bryan E Welm, Michael T Lewis, Bingliang Fang, Jack A Roth, Funda Meric-Bernstam, Meenhard Herylyn, Michael A Davies, Li Ding, Shunqiang Li, Ramaswamy Govindan, Claudio Isella, Jeffrey A Moscow, Livio Trusolino, Annette T Byrne, Jos Jonkers, Carol J Bult, Enzo Medico, Jeffrey H Chuang, null null, null null
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts. Nature genetics 53 (1) (2021)
Barbara Lupo, Francesco Sassi, Marika Pinnelli, Francesco Galimi, Eugenia R Zanella, Valentina Vurchio, Giorgia Migliardi, Paolo Armando Gagliardi, Alberto Puliafito, Daria Manganaro, Paolo Luraghi, Michael Kragh, Mikkel W Pedersen, Ivan D Horak, Carla Boccaccio, Enzo Medico, Luca Primo, Daniel Nichol, Inmaculada Spiteri, Timon Heide, Alexandra Vatsiou, Trevor A Graham, Elena Élez, Guillem Argiles, Paolo G Nuciforo, Andrea Sottoriva, Rodrigo Dienstmann, Diego Pasini, Elena Grassi, Claudio Isella, Andrea Bertotti, Livio Trusolino
Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell-like phenotype. Science translational medicine 12 (555) (2021)
Bas Ponsioen, Jasmin B Post, Julian R Buissant des Amorie, Dimitrios Laskaris, Ravian L van Ineveld, Simone Kersten, Andrea Bertotti, Francesco Sassi, François Sipieter, Benjamin Cappe, Sander Mertens, Ingrid Verlaan-Klink, Sylvia F Boj, Rob G J Vries, Holger Rehmann, Peter Vandenabeele, Franck B Riquet, Livio Trusolino, Johannes L Bos, Hugo J G Snippert
Quantifying single-cell ERK dynamics in colorectal cancer organoids reveals EGFR as an amplifier of oncogenic MAPK pathway signalling. Nature cell biology 23 (4) (2021)
Elisa Fontana, Gift Nyamundanda, David Cunningham, Dongsheng Tu, Maggie Chon U Cheang, Derek J Jonker, Lillian L Siu, Francesco Sclafani, Katherine Eason, Chanthirika Ragulan, Maria Antonietta Bali, Sanna Hulkki-Wilson, Jonathan M Loree, Paul M Waring, Mirella Giordano, Patrick Lawrence, Daniel Nava Rodrigues, Ruwaida Begum, Jeremy D Shapiro, Timothy J Price, Chiara Cremolini, Naureen Starling, Filippo Pietrantonio, Livio Trusolino, Christopher J O'Callaghan, Anguraj Sadanandam
Intratumoral Transcriptome Heterogeneity Is Associated With Patient Prognosis and Sidedness in Patients With Colorectal Cancer Treated With Anti-EGFR Therapy From the CO.20 Trial. JCO precision oncology 4 (2020)
Andreas U Lindner, Steven Carberry, Naser Monsefi, Ana Barat, Manuela Salvucci, Robert O'Byrne, Eugenia R Zanella, Mattia Cremona, Bryan T Hennessy, Andrea Bertotti, Livio Trusolino, Jochen H M Prehn
Systems analysis of protein signatures predicting cetuximab responses in KRAS, NRAS, BRAF and PIK3CA wild-type patient-derived xenograft models of metastatic colorectal cancer. International journal of cancer 147 (10) (2020)
Mariangela Russo, Giovanni Crisafulli, Alberto Sogari, Nicole M Reilly, Sabrina Arena, Simona Lamba, Alice Bartolini, Vito Amodio, Alessandro Magrì, Luca Novara, Ivana Sarotto, Zachary D Nagel, Cortt G Piett, Alessio Amatu, Andrea Sartore-Bianchi, Salvatore Siena, Andrea Bertotti, Livio Trusolino, Mattia Corigliano, Marco Gherardi, Marco Cosentino Lagomarsino, Federica Di Nicolantonio, Alberto Bardelli
Adaptive mutability of colorectal cancers in response to targeted therapies. Science (New York, N.Y.) 366 (6472) (2019)

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