Safety of dihydroartemisinin-piperaquine versus artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria among children in Africa: a systematic review and meta-analysis of randomized control trials.
Dawit Getachew AssefaEden Dagnachew ZelekeWondwosen MollaNebiyu MengistuAhmedin SefaAndualem MebratuAsresu Feleke BateEtaferaw BekeleGizachew YesmawEyasu MakonnenPublished in: Malaria journal (2022)
From this review, it can be concluded that early vomiting, diarrhoea, and cough were common were significantly more frequent in patients who were treated with the DHA-PQ than that of AL, and both drugs are well tolerated. More studies comparing AL with DHA-PQ are needed to determine the comparative safety of these drugs.