Midlife adiposity predicts cognitive decline in the prospective Multicenter AIDS Cohort Study.
Leah H RubinDeborah GustafsonKellie L HawkinsLong ZhangLisa P JacobsonJames T BeckerCynthia A MunroJordan E LakeEileen MartinAndrew LevineTodd T BrownNed SacktorKristine M ErlandsonPublished in: Neurology (2019)
Higher adiposity is associated with lower cognition cross-sectionally and greater cognitive decline, particularly in HIV- men. Overweight and obesity may be important predictors of neurologic outcomes and avenues for prevention and intervention.
Keyphrases
- cognitive decline
- mild cognitive impairment
- antiretroviral therapy
- insulin resistance
- hiv infected
- hiv positive
- human immunodeficiency virus
- randomized controlled trial
- hiv aids
- weight gain
- hiv testing
- hepatitis c virus
- men who have sex with men
- middle aged
- cross sectional
- double blind
- metabolic syndrome
- adipose tissue
- skeletal muscle
- clinical trial
- physical activity