Altered human alveolar bone gene expression in type 2 diabetes-A cross-sectional study.

Srinivas AyilavarapuAbbas DoctorChun-Teh LeeGena D TribbleYulun ChiuRobin L WeltmanNikola Angelov

Published in: Journal of periodontal research (2021)

Altered expression of genes due to downregulation of certain pathways that are involved in bone turnover and inflammation suggests that overall wound healing and bone homeostasis may be compromised in type 2 diabetes.

Keyphrases

type diabetes
bone mineral density
gene expression
postmenopausal women
soft tissue
wound healing
endothelial cells
bone loss
glycemic control
poor prognosis
oxidative stress
dna methylation
cardiovascular disease
insulin resistance
physical activity
genome wide
induced pluripotent stem cells
pluripotent stem cells