Advanced glycation end-products increase IL-6 and ICAM-1 expression via RAGE, MAPK and NF-κB pathways in human gingival fibroblasts.

K NonakaY KajiuraM BandoE SakamotoY InagakiJ H LewKoji NaruishiT IkutaK YoshidaT KobayashiH YoshieT NagataJun Kido

Published in: Journal of periodontal research (2017)

AGEs increase IL-6 and ICAM-1 expression via the RAGE, MAPK and NF-κB pathways in HGFs and may exacerbate the progression of the pathogenesis of periodontal diseases.

Keyphrases

signaling pathway
pi k akt
poor prognosis
oxidative stress
lps induced
binding protein
cell proliferation
long non coding rna
inflammatory response
extracellular matrix
pluripotent stem cells
toll like receptor