Isolated Hepatic Perfusion With Melphalan for Patients With Isolated Uveal Melanoma Liver Metastases: A Multicenter, Randomized, Open-Label, Phase III Trial (the SCANDIUM Trial).
Roger Olofsson BaggeAxel NelsonAmir ShafazandCharlotta All-ErikssonChristian CahlinHakon BlomstrandHildur HelgadottirJens Folke KiilgaardSara KinhultIngrid LjuslinderJan MattssonMagnus RizellMalin Sternby EilardGustav J UllenhagJonas Andreas NilssonLars NyPer LindnérPublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
IHP treatment resulted in superior ORR, hPFS, and PFS compared with best alternative care in previously untreated patients with isolated liver metastases from primary uveal melanoma.
Keyphrases
- phase iii
- liver metastases
- open label
- double blind
- phase ii
- clinical trial
- placebo controlled
- phase ii study
- study protocol
- healthcare
- palliative care
- high dose
- skin cancer
- randomized controlled trial
- squamous cell carcinoma
- magnetic resonance imaging
- computed tomography
- chronic pain
- cross sectional
- rectal cancer
- pain management
- basal cell carcinoma
- combination therapy