Protocol for a phase IV double-blind randomised controlled trial to investigate the effect of the 13-valent pneumococcal conjugate vaccine and the 23-valent pneumococcal polysaccharide vaccine on pneumococcal colonisation using the experimental human pneumococcal challenge model in healthy adults (PREVENTING PNEUMO 2).
Konstantinos LiatsikosAngela Hyder-WrightSherin PojarTao ChenDuo-Lao WangKelly DaviesChristopher MyerscoughJesus ReineRyan E RobinsonBritta UrbanElena MitsiCarla SolorzanoStephen B GordonAngela QuinnKaijie PanAnnaliesa S AndersonChristian TheilackerElizabeth BegierBradford D GessnerAndrea CollinsDaniela M Ferreiranull nullPublished in: BMJ open (2022)
ISRCTN15728847, NCT04974294.