Association between XRCC3 rs861539 Polymorphism and the Risk of Ovarian Cancer: Meta-Analysis and Trial Sequential Analysis.

Siya HuYunnan JingFang-Yuan Liu Feng-Juan Han

Published in: BioMed research international (2022)

This meta-analysis showed a significant association between XRCC3 rs861539 polymorphism and ovarian cancer risk, especially in Caucasians. Large-scale multicenter case-control studies in more different regions will be needed in the future.

Keyphrases

case control
systematic review
dna repair
meta analyses
clinical trial
study protocol
current status
randomized controlled trial
phase ii
cross sectional
oxidative stress
double blind