Assessing the effects of probiotic supplementation, single strain versus mixed strains, on femoral mineral density and osteoblastic gene mRNA expression in rats.
Maria ParvanehRosita JamaluddinMahdi EbrahimiGolgis KarimiMohd Redzwan SabranPublished in: Journal of bone and mineral metabolism (2024)
Supplementation with B. longum and L. helveticus significantly reduces bone resorption and improves bone health in OVX rats, with single-strain supplementation showing greater efficacy compared to a mixed-strain combination. These findings highlight the potential of probiotics as a therapeutic intervention for osteoporosis, warranting further investigation in human studies.
Keyphrases
- bone mineral density
- postmenopausal women
- bone loss
- endothelial cells
- randomized controlled trial
- healthcare
- public health
- escherichia coli
- soft tissue
- human health
- copy number
- body composition
- induced pluripotent stem cells
- risk assessment
- climate change
- dna methylation
- genome wide identification
- social media
- lactic acid
- health promotion