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A novel method to efficiently differentiate human osteoclasts from blood-derived monocytes.

Suganja ChandrabalanLinh DangUwe HansenMelanie TimmenCorinna WehmeyerRichard StangeTim BeißbarthClaudia BinderAnnalen BleckmannKerstin Menck
Published in: Biological procedures online (2024)
Our study has established a novel protocol for the isolation of primary human osteoclasts that improves osteoclastogenesis in comparison to the conventionally used cultivation approach.
Keyphrases
  • endothelial cells
  • induced pluripotent stem cells
  • bone loss
  • randomized controlled trial
  • pluripotent stem cells
  • dendritic cells
  • peripheral blood
  • immune response