Multicenter Validation of Association Between Decline in MRI-PDFF and Histologic Response in NASH.

Stephen CaldwellBrent A Neuschwander-TetriArun SanyalNaga ChalasaniAnna Mae DiehlNorah A TerraultKris KowdleySrinivasan DasarathyDavid KleinerCynthia BehlingJoel LavineMark Van NattaMichael MiddletonJames TonasciaClaude Sirlinnull null

Published in: Hepatology (Baltimore, Md.) (2020)

OCA was better than placebo in reducing liver fat. This multicenter trial provides data regarding the association between 30% decline in MRI-PDFF relative to baseline and histologic response in NASH.

Keyphrases

contrast enhanced
magnetic resonance imaging
double blind
diffusion weighted imaging
cross sectional
study protocol
electronic health record
magnetic resonance
machine learning
fatty acid
artificial intelligence
open label