The effects of losartan on cytomegalovirus infection in human trabecular meshwork cells.
Jin A ChoiJu-Eun KimHyun-Hee JuJiyoung LeeDonghyun JeeChan Kee ParkSoon-Young PaikPublished in: PloS one (2019)
Losartan inhibited the expression of TGF-β1 and fibrogenic molecules in human TM cells. Thus, losartan has the potential to decrease TM fibrosis in patients with CMV-induced hypertensive anterior uveitis.
Keyphrases
- induced apoptosis
- endothelial cells
- cell cycle arrest
- angiotensin ii
- high glucose
- poor prognosis
- blood pressure
- induced pluripotent stem cells
- endoplasmic reticulum stress
- pluripotent stem cells
- cell death
- rheumatoid arthritis
- signaling pathway
- bone mineral density
- transforming growth factor
- pi k akt
- body composition
- human health