Locus Coeruleus Shows a Spatial Pattern of Structural Disintegration in Parkinson's Disease.

Christopher Fugl MadelungDavid MederSøren A FuglsangMarta M MarquesVincent O BoerKristoffer H MadsenEsben T PetersenAnne-Mette HejlAnnemette LøkkegaardHartwig R Siebner

Published in: Movement disorders : official journal of the Movement Disorder Society (2022)

A spatially heterogeneous disintegration of LC in PD may determine the individual expression of specific nonmotor symptoms such as orthostatic dysregulation or apathy. © 2022 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson Movement Disorder Society.

Keyphrases

poor prognosis
parkinson disease
simultaneous determination
binding protein
sleep quality
randomized controlled trial
systematic review
long non coding rna
depressive symptoms
meta analyses