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Prevalence, causes and impact of TP53-loss phenocopying events in human tumors.

Bruno Fito-LopezMarina SalvadoresMiguel-Martin AlvarezFran Supek
Published in: BMC biology (2023)
Human tumors that do not bear obvious TP53 genetic alterations but that phenocopy p53 activity loss are common, and the USP28 gene deletions are one likely cause.
Keyphrases
  • endothelial cells
  • induced pluripotent stem cells
  • genome wide
  • risk factors
  • pluripotent stem cells
  • gene expression
  • transcription factor