Fran Supek

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 43

Top Venues

Nature communications

Nucleic acids research

Nature genetics

BMC biology

Instituciò Catalana de Recerca i Estudis Avancats

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Instituciò Catalana de Recerca i Estudis Avancats Nov 01 2018

Spain

ICREA Research Professor :: Group Leader at IRB Barcelona

Institute for Research in Biomedicine (IRB) Apr 01 2017 - Oct 31 2018

Spain

Group Leader / Ramon y Cajal fellow :: Structural and Computational Biology

Rudjer Boskovic Institute

Croatia

Research Associate, part-time :: Division for Electronics

Centre for Genomic Regulation (CRG) Dec 01 2010 - Dec 31 2016

Spain

postdoctoral researcher / Marie Curie fellow :: EMBL/CRG Systems Biology Unit

Publications

Marina Salvadores, Fran Supek
Cell cycle gene alterations associate with a redistribution of mutation risk across chromosomal domains in human cancers. Nature cancer (2024)
David Mas-Ponte, Fran Supek
Mutation rate heterogeneity at the sub-gene scale due to local DNA hypomethylation. Nucleic acids research (2024)
Elizaveta Besedina, Fran Supek
Copy number losses of oncogenes and gains of tumor suppressor genes generate common driver mutations. Nature communications 15 (1) (2024)
David Mas-Ponte, Fran Supek
Mutation rate heterogeneity at the sub-gene scale due to local DNA hypomethylation. Nucleic acids research 52 (8) (2024)
Marina Salvadores, Fran Supek
Cell cycle gene alterations associate with a redistribution of mutation risk across chromosomal domains in human cancers. Nature cancer 5 (2) (2024)
Ignasi Toledano, Fran Supek, Ben Lehner
Genome-scale quantification and prediction of pathogenic stop codon readthrough by small molecules. Nature genetics (2024)
Elizaveta Besedina, Fran Supek
Copy number losses of oncogenes and gains of tumor suppressor genes generate common driver mutations. Nature communications 15 (1) (2024)
David Mas-Ponte, Fran Supek
Mutation rate heterogeneity at the sub-gene scale due to local DNA hypomethylation. Nucleic acids research 52 (8) (2024)
Irene Franco, Fran Supek
Genomics reveal unknown mutation-promoting agents at global sites. Nature 629 (8013) (2024)
Elizaveta Besedina, Fran Supek
Copy number losses of oncogenes and gains of tumor suppressor genes generate common driver mutations. Nature communications 15 (1) (2024)
Irene Franco, Fran Supek
Genomics reveal unknown mutation-promoting agents at global sites. Nature 629 (8013) (2024)
David Mas-Ponte, Fran Supek
Mutation rate heterogeneity at the sub-gene scale due to local DNA hypomethylation. Nucleic acids research 52 (8) (2024)
Marina Salvadores, Fran Supek
Cell cycle gene alterations associate with a redistribution of mutation risk across chromosomal domains in human cancers. Nature cancer 5 (2) (2024)
Irene Franco, Fran Supek
Genomics reveal unknown mutation-promoting agents at global sites. Nature 629 (8013) (2024)
Marina Salvadores, Fran Supek
Cell cycle gene alterations associate with a redistribution of mutation risk across chromosomal domains in human cancers. Nature cancer (2024)
David Mas-Ponte, Fran Supek
Mutation rate heterogeneity at the sub-gene scale due to local DNA hypomethylation. Nucleic acids research 52 (8) (2024)
Bruno Fito-Lopez, Marina Salvadores, Miguel-Martin Alvarez, Fran Supek
Prevalence, causes and impact of TP53-loss phenocopying events in human tumors. BMC biology 21 (1) (2023)
Bruno Fito-Lopez, Marina Salvadores, Miguel-Martin Alvarez, Fran Supek
Prevalence, causes and impact of TP53-loss phenocopying events in human tumors. BMC biology 21 (1) (2023)
Bruno Fito-Lopez, Marina Salvadores, Miguel-Martin Alvarez, Fran Supek
Prevalence, causes and impact of TP53-loss phenocopying events in human tumors. BMC biology 21 (1) (2023)
Bruno Fito-Lopez, Marina Salvadores, Miguel-Martin Alvarez, Fran Supek
Prevalence, causes and impact of TP53-loss phenocopying events in human tumors. BMC biology 21 (1) (2023)
Mischan Vali-Pour, Solip Park, Jose Espinosa-Carrasco, Daniel Ortiz-Martínez, Ben Lehner, Fran Supek
Author Correction: The impact of rare germline variants on human somatic mutation processes. Nature communications 14 (1) (2023)
Bernardo Rodriguez-Martin, Eva G Alvarez, Adrian Baez-Ortega, Jorge Zamora, Fran Supek, Jonas Demeulemeester, Martin Santamarina, Young Seok Ju, Javier Temes, Daniel Garcia Souto, Harald Detering, Yilong Li, Jorge Rodriguez-Castro, Ana Dueso-Barroso, Alicia L Bruzos, Stefan C Dentro, Miguel G Blanco, Gianmarco Contino, Daniel Ardeljan, Marta Tojo, Nicola D Roberts, Sonia Zumalave, Paul A W Edwards, Joachim Weischenfeldt, Montserrat Puiggròs, Zechen Chong, Ken Chen, Eunjung Alice Lee, Jeremiah A Wala, Keiran M Raine, Adam Butler, Sebastian M Waszak, Fábio C P Navarro, Steven E Schumacher, Jean Monlong, Francesco Maura, Niccolo Bolli, Guillaume Bourque, Mark Gerstein, Peter J Park, David C Wedge, Rameen Beroukhim, David Torrents, Jan O Korbel, Iñigo Martincorena, Rebecca C Fitzgerald, Peter Van Loo, Haig H Kazazian, Kathleen H Burns, null null, Peter J Campbell, Jose M C Tubio, null null
Author Correction: Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition. Nature genetics (2023)
Bruno Fito-Lopez, Marina Salvadores, Miguel-Martin Alvarez, Fran Supek
Prevalence, causes and impact of TP53-loss phenocopying events in human tumors. BMC biology 21 (1) (2023)
Mischan Vali-Pour, Ben Lehner, Fran Supek
The impact of rare germline variants on human somatic mutation processes. Nature communications 13 (1) (2022)
Aleksandra Karolak, Jurica Levatić, Fran Supek
A framework for mutational signature analysis based on DNA shape parameters. PloS one 17 (1) (2022)
Miguel Martín Álvarez, Josep Biayna, Fran Supek
TP53-dependent toxicity of CRISPR/Cas9 cuts is differential across genomic loci and can confound genetic screening. Nature communications 13 (1) (2022)
David Mas-Ponte, Marcel McCullough, Fran Supek
Spectrum of DNA mismatch repair failures viewed through the lens of cancer genomics and implications for therapy. Clinical science (London, England : 1979) 136 (5) (2022)
Sami Belhadj, Aliya Khurram, Chaitanya Bandlamudi, Guillermo Palou-Márquez, Vignesh Ravichandran, Zoe Steinsnyder, Temima Wildman, Amanda Catchings, Yelena M Kemel, Semanti Mukherjee, Benjamin Fesko, Kanika S Arora, Miika Mehine, Sita Dandiker, Aalin Izhar, John H J Petrini, Susan M Domchek, Katherine L Nathanson, Jamie Brower, Fergus J Couch, Zsofia K Stadler, Mark E Robson, Michael F Walsh, Joseph Vijai, Michael F Berger, Fran Supek, Rachid Karam, Sabine Topka, Kenneth Offit
NBN pathogenic germline variants are associated with pan-cancer susceptibility and in vitro DNA damage response defects. Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Jurica Levatić, Marina Salvadores, Francisco Fuster-Tormo, Fran Supek
Mutational signatures are markers of drug sensitivity of cancer cells. Nature communications 13 (1) (2022)
Solip Park, Fran Supek, Ben Lehner
Higher order genetic interactions switch cancer genes from two-hit to one-hit drivers. Nature communications 12 (1) (2021)
Josep Biayna, Isabel Garcia-Cao, Miguel M Álvarez, Marina Salvadores, Jose Espinosa-Carrasco, Marcel McCullough, Fran Supek, Travis H Stracker
Loss of the abasic site sensor HMCES is synthetic lethal with the activity of the APOBEC3A cytosine deaminase in cancer cells. PLoS biology 19 (3) (2021)
Joshua S Madin, Daniel Aagren Nielsen, Maria Brbic, Ross Corkrey, David Danko, Kyle Edwards, Martin K M Engqvist, Noah Fierer, Jemma L Geoghegan, Michael R Gillings, Nikos C Kyrpides, Elena Litchman, Christopher E Mason, Lisa R Moore, Søren Laurentius Nielsen, Ian T Paulsen, Nathan D Price, T B K Reddy, Matthew A Richards, Eduardo P C Rocha, Thomas M Schmidt, Heba Shaaban, Maulik Shukla, Fran Supek, Sasha G Tetu, Sara Vieira-Silva, Alice R Wattam, David A Westfall, Mark Westoby
A synthesis of bacterial and archaeal phenotypic trait data. Scientific data 7 (1) (2020)
Marina Salvadores, Francisco Fuster-Tormo, Fran Supek
Matching cell lines with cancer type and subtype of origin via mutational, epigenomic, and transcriptomic patterns. Science advances 6 (27) (2020)
Bernardo Rodriguez-Martin, Eva G Alvarez, Adrian Baez-Ortega, Jorge Zamora, Fran Supek, Jonas Demeulemeester, Martin Santamarina, Young Seok Ju, Javier Temes, Daniel Garcia Souto, Harald Detering, Yilong Li, Jorge Rodriguez-Castro, Ana Dueso-Barroso, Alicia L Bruzos, Stefan C Dentro, Miguel G Blanco, Gianmarco Contino, Daniel Ardeljan, Marta Tojo, Nicola D Roberts, Sonia Zumalave, Paul A W Edwards, Joachim Weischenfeldt, Montserrat Puiggròs, Zechen Chong, Ken Chen, Eunjung Alice Lee, Jeremiah A Wala, Keiran M Raine, Adam Butler, Sebastian M Waszak, Fábio C P Navarro, Steven E Schumacher, Jean Monlong, Francesco Maura, Niccolo Bolli, Guillaume Bourque, Mark Gerstein, Peter J Park, David C Wedge, Rameen Beroukhim, David Torrents, Jan O Korbel, Inigo Martincorena, Rebecca C Fitzgerald, Peter Van Loo, Haig H Kazazian, Kathleen H Burns, null null, Peter J Campbell, Jose M C Tubio, null null
Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition. Nature genetics 52 (3) (2020)
David Mas-Ponte, Fran Supek
DNA mismatch repair promotes APOBEC3-mediated diffuse hypermutation in human cancers. Nature genetics 52 (9) (2020)
Marina Salvadores, David Mas-Ponte, Fran Supek
Passenger mutations accurately classify human tumors. PLoS computational biology 15 (4) (2019)
Matej Mihelčić, Tomislav Šmuc, Fran Supek
Patterns of diverse gene functions in genomic neighborhoods predict gene function and phenotype. Scientific reports 9 (1) (2019)
Rik G H Lindeboom, Michiel Vermeulen, Ben Lehner, Fran Supek
The impact of nonsense-mediated mRNA decay on genetic disease, gene editing and cancer immunotherapy. Nature genetics 51 (11) (2019)
Alexandra Avgustinova, Aikaterini Symeonidi, Andrés Castellanos, Uxue Urdiroz-Urricelqui, Llorenç Solé-Boldo, Mercè Martín, Ivan Pérez-Rodríguez, Neus Prats, Ben Lehner, Fran Supek, Salvador Aznar Benitah
Loss of G9a preserves mutation patterns but increases chromatin accessibility, genomic instability and aggressiveness in skin tumours. Nature cell biology 20 (12) (2018)
Vedrana Vidulin, Tomislav Šmuc, Sašo Džeroski, Fran Supek
The evolutionary signal in metagenome phyletic profiles predicts many gene functions. Microbiome 6 (1) (2018)
Jelena Repar, Fran Supek, Tin Klanjšček, Tobias Warnecke, Ksenija Zahradka, Davor Zahradka
Elevated Rate of Genome Rearrangements in Radiation-Resistant Bacteria. Genetics 205 (4) (2017)
Rik G H Lindeboom, Fran Supek, Ben Lehner
The rules and impact of nonsense-mediated mRNA decay in human cancers. Nature genetics 48 (10) (2016)
Maria Brbić, Matija Piškorec, Vedrana Vidulin, Anita Kriško, Tomislav Šmuc, Fran Supek
The landscape of microbial phenotypic traits and associated genes. Nucleic acids research 44 (21) (2016)

Fran Supek.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Fran Supek