The Mini-Organo: A rapid high-throughput 3D coculture organotypic assay for oncology screening and drug development.

Jessica L Chitty Joanna N Skhinas Elysse C FilipeShan WangCarmen Rodriguez CupelloRhiannon D GrantMichelle YamMichael PapanicolaouGretel MajorAnaiis ZaratzianAndrew M Da SilvaMichael TayaoClaire Vennin Paul Timpson Chris Denis Madsen Thomas R Cox

Published in: Cancer reports (Hoboken, N.J.) (2019)

The Mini-Organo high-throughput 3D organotypic assay allows the rapid screening of potential cancer therapeutics in human and mouse models in a time-efficient manner.

Keyphrases

high throughput
single cell
endothelial cells
mouse model
papillary thyroid
loop mediated isothermal amplification
palliative care
squamous cell carcinoma
pluripotent stem cells
risk assessment
young adults
human health
childhood cancer
climate change
sensitive detection
lymph node metastasis