Paul Timpson

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 30

Top Topics

Tyrosine Kinase

Finite Element Analysis

Brain Metastases

Top Venues

Science advances

Nature cell biology

This page only lists publications with an associated author ORCID identifier.

Publications

Brooke A Pereira, Shona Ritchie, Cecilia R Chambers, Katie A Gordon, Astrid Magenau, Kendelle J Murphy, Max Nobis, Victoria M Tyma, Ying Fei Liew, Morghan C Lucas, Marjan Mojtabavi Naeini, Deborah S Barkauskas, Diego Chacon-Fajardo, Anna E Howell, Amelia L Parker, Sean C Warren, Daniel A Reed, Victoria Lee, Xanthe L Metcalf, Young-Kyung Lee, Luke P O'Regan, Jessie Zhu, Michael Trpceski, Angela R M Kurz, Janett Stoehr, Romain Rouet, Xufeng Lin, Jessica L Chitty, Sean Porazinski, Sunny Z Wu, Elysse C Filipe, Antonia L Cadell, Holly Holliday, Jessica Yang, Michael Papanicolaou, Ruth J Lyons, Anaiis Zaratzian, Michael Tayao, Andrew Da Silva, Claire Vennin, Julia X Yin, Alysha B Dew, Paul J McMillan, Leonard D Goldstein, Ira W Deveson, David R Croucher, Michael Susithiran Samuel, Hao-Wen Sim, Marcel Batten, Lorraine A Chantrill, Sean M Grimmond, Anthony J Gill, Jaswinder Samra, Thomas R Jeffry Evans, Takako Sasaki, Tri Giang Phan, Alexander Swarbrick, Owen James Sansom, Jennifer P Morton, null null, null null, Marina Pajic, Benjamin L Parker, David Herrmann, Thomas R Cox, Paul Timpson
Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response. Science advances 10 (27) (2024)
Brooke A Pereira, Shona Ritchie, Cecilia R Chambers, Katie A Gordon, Astrid Magenau, Kendelle J Murphy, Max Nobis, Victoria M Tyma, Ying Fei Liew, Morghan C Lucas, Marjan Mojtabavi Naeini, Deborah S Barkauskas, Diego Chacon-Fajardo, Anna E Howell, Amelia L Parker, Sean C Warren, Daniel A Reed, Victoria Lee, Xanthe L Metcalf, Young-Kyung Lee, Luke P O'Regan, Jessie Zhu, Michael Trpceski, Angela R M Kurz, Janett Stoehr, Romain Rouet, Xufeng Lin, Jessica L Chitty, Sean Porazinski, Sunny Z Wu, Elysse C Filipe, Antonia L Cadell, Holly Holliday, Jessica Yang, Michael Papanicolaou, Ruth J Lyons, Anaiis Zaratzian, Michael Tayao, Andrew Da Silva, Claire Vennin, Julia X Yin, Alysha B Dew, Paul J McMillan, Leonard D Goldstein, Ira W Deveson, David R Croucher, Michael Susithiran Samuel, Hao-Wen Sim, Marcel Batten, Lorraine A Chantrill, Sean M Grimmond, Anthony J Gill, Jaswinder Samra, Thomas R Jeffry Evans, Takako Sasaki, Tri Giang Phan, Alexander Swarbrick, Owen James Sansom, Jennifer P Morton, null null, null null, Marina Pajic, Benjamin L Parker, David Herrmann, Thomas R Cox, Paul Timpson
Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response. Science advances 10 (27) (2024)
Robert J Ju, Alistair D Falconer, Christanny J Schmidt, Marco A Enriquez Martinez, Kevin M Dean, Reto P Fiolka, David P Sester, Max Nobis, Paul Timpson, Alexis J Lomakin, Gaudenz Karl Danuser, Melanie D White, Nikolas K Haass, Dietmar B Oelz, Samantha J Stehbens
Compression-dependent microtubule reinforcement enables cells to navigate confined environments. Nature cell biology (2024)
Robert J Ju, Alistair D Falconer, Christanny J Schmidt, Marco A Enriquez Martinez, Kevin M Dean, Reto P Fiolka, David P Sester, Max Nobis, Paul Timpson, Alexis J Lomakin, Gaudenz Karl Danuser, Melanie D White, Nikolas K Haass, Dietmar B Oelz, Samantha J Stehbens
Compression-dependent microtubule reinforcement enables cells to navigate confined environments. Nature cell biology (2024)
Brooke A Pereira, Shona Ritchie, Cecilia R Chambers, Katie A Gordon, Astrid Magenau, Kendelle J Murphy, Max Nobis, Victoria M Tyma, Ying Fei Liew, Morghan C Lucas, Marjan Mojtabavi Naeini, Deborah S Barkauskas, Diego Chacon-Fajardo, Anna E Howell, Amelia L Parker, Sean C Warren, Daniel A Reed, Victoria Lee, Xanthe L Metcalf, Young-Kyung Lee, Luke P O'Regan, Jessie Zhu, Michael Trpceski, Angela R M Kurz, Janett Stoehr, Romain Rouet, Xufeng Lin, Jessica L Chitty, Sean Porazinski, Sunny Z Wu, Elysse C Filipe, Antonia L Cadell, Holly Holliday, Jessica Yang, Michael Papanicolaou, Ruth J Lyons, Anaiis Zaratzian, Michael Tayao, Andrew Da Silva, Claire Vennin, Julia X Yin, Alysha B Dew, Paul J McMillan, Leonard D Goldstein, Ira W Deveson, David R Croucher, Michael Susithiran Samuel, Hao-Wen Sim, Marcel Batten, Lorraine A Chantrill, Sean M Grimmond, Anthony J Gill, Jaswinder Samra, Thomas R Jeffry Evans, Takako Sasaki, Tri Giang Phan, Alexander Swarbrick, Owen James Sansom, Jennifer P Morton, null null, null null, Marina Pajic, Benjamin L Parker, David Herrmann, Thomas R Cox, Paul Timpson
Temporally resolved proteomics identifies nidogen-2 as a cotarget in pancreatic cancer that modulates fibrosis and therapy response. Science advances 10 (27) (2024)
James R W Conway, Sean C Warren, Young-Kyung Lee, Andrew T McCulloch, Astrid Magenau, Victoria Lee, Xanthe L Metcalf, Janett Stoehr, Katharina Haigh, Lea Abdulkhalek, Cristian S Guaman, Daniel A Reed, Kendelle J Murphy, Brooke A Pereira, Pauline Mélénec, Cecilia R Chambers, Sharissa L Latham, Helen Lenthall, Elissa K Deenick, Yuanqing Ma, Tri Giang Phan, Elgene Lim, Anthony M Joshua, Stacey N Walters, Shane T Grey, Yan-Chuan Shi, Lei Zhang, Herbert Herzog, David R Croucher, Andy Philp, Colinda L G J Scheele, David Herrmann, Owen James Sansom, Jennifer P Morton, Antonella Papa, Jody Jonathan Haigh, Max Nobis, Paul Timpson
Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse. Science advances 9 (17) (2023)
James R W Conway, Sean C Warren, Young-Kyung Lee, Andrew T McCulloch, Astrid Magenau, Victoria Lee, Xanthe L Metcalf, Janett Stoehr, Katharina Haigh, Lea Abdulkhalek, Cristian S Guaman, Daniel A Reed, Kendelle J Murphy, Brooke A Pereira, Pauline Mélénec, Cecilia R Chambers, Sharissa L Latham, Helen Lenthall, Elissa K Deenick, Yuanqing Ma, Tri Giang Phan, Elgene Lim, Anthony M Joshua, Stacey N Walters, Shane T Grey, Yan-Chuan Shi, Lei Zhang, Herbert Herzog, David R Croucher, Andy Philp, Colinda L G J Scheele, David Herrmann, Owen James Sansom, Jennifer P Morton, Antonella Papa, Jody Jonathan Haigh, Max Nobis, Paul Timpson
Monitoring AKT activity and targeting in live tissue and disease contexts using a real-time Akt-FRET biosensor mouse. Science advances 9 (17) (2023)
Nayan Deger Bhattacharyya, Wunna Kyaw, Michelle M McDonald, Rama Dhenni, Abigail K Grootveld, Ya Xiao, Ryan Chai, Weng Hua Khoo, Linda C Danserau, C Marcelo Sergio, Paul Timpson, Woei Ming Lee, Peter I Croucher, Tri Giang Phan
Minimally invasive longitudinal intravital imaging of cellular dynamics in intact long bone. Nature protocols (2023)
Rebeca Uceda-Castro, Andreia S Margarido, Ji-Ying Song, Mark Cornelis de Gooijer, Hendrik A Messal, Cecilia R Chambers, Max Nobis, Ceren H Çitirikkaya, Kerstin Hahn, Danielle Seinstra, David Herrmann, Paul Timpson, Pieter Wesseling, Olaf van Tellingen, Claire Vennin, Jacco van Rheenen
BCRP drives intrinsic chemoresistance in chemotherapy-naïve breast cancer brain metastasis. Science advances 9 (42) (2023)
Jessica L Chitty, Michelle Yam, Lara Perryman, Amelia L Parker, Joanna N Skhinas, Yordanos F I Setargew, Ellie T Y Mok, Emmi Tran, Rhiannon D Grant, Sharissa L Latham, Brooke A Pereira, Shona C Ritchie, Kendelle J Murphy, Michael Trpceski, Alison D Findlay, Pauline Melenec, Elysse C Filipe, Audrey Nadalini, Sipiththa Velayuthar, Gretel S Major, Kaitlin Wyllie, Michael Papanicolaou, Shivanjali Ratnaseelan, Phoebe A Phillips, George Sharbeen, Janet Youkhana, Alice Russo, Antonia Blackwell, Jordan F Hastings, Morghan C Lucas, Cecilia R Chambers, Daniel A Reed, Janett Stoehr, Claire Vennin, Ruth Pidsley, Anaiis Zaratzian, Andrew M Da Silva, Michael Tayao, Brett Charlton, David Herrmann, Max Nobis, Susan J Clark, Andrew V Biankin, Amber L Johns, David R Croucher, Adnan Nagrial, Anthony J Gill, Sean M Grimmond, null null, null null, Marina Pajic, Paul Timpson, Wolfgang Jarolimek, Thomas R Cox
A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer. Nature cancer (2023)
Jordan F Hastings, Sharissa L Latham, Alvin Kamili, Madeleine S Wheatley, Jeremy Z R Han, Marie Wong, Monica Phimmachanh, Max Nobis, Chiara Pantarelli, Antonia L Cadell, Yolande E I O'Donnell, King Ho Leong, Sophie Lynn, Fan-Suo Geng, Lujing Cui, Sabrina Yan, Joanna Achinger-Kawecka, Clare Stirzaker, Murray D Norris, Michelle Haber, Toby N Trahair, Frank Speleman, Katleen De Preter, Mark J Cowley, Ozren Bogdanovic, Paul Timpson, Thomas R Cox, Walter Kolch, Jamie I Fletcher, Dirk Fey, David R Croucher
Memory of stochastic single-cell apoptotic signaling promotes chemoresistance in neuroblastoma. Science advances 9 (9) (2023)
Jordan F Hastings, Sharissa L Latham, Alvin Kamili, Madeleine S Wheatley, Jeremy Z R Han, Marie Wong, Monica Phimmachanh, Max Nobis, Chiara Pantarelli, Antonia L Cadell, Yolande E I O'Donnell, King Ho Leong, Sophie Lynn, Fan-Suo Geng, Lujing Cui, Sabrina Yan, Joanna Achinger-Kawecka, Clare Stirzaker, Murray D Norris, Michelle Haber, Toby N Trahair, Frank Speleman, Katleen De Preter, Mark J Cowley, Ozren Bogdanovic, Paul Timpson, Thomas R Cox, Walter Kolch, Jamie I Fletcher, Dirk Fey, David R Croucher
Memory of stochastic single-cell apoptotic signaling promotes chemoresistance in neuroblastoma. Science advances 9 (9) (2023)
Jordan F Hastings, Sharissa L Latham, Alvin Kamili, Madeleine S Wheatley, Jeremy Z R Han, Marie Wong, Monica Phimmachanh, Max Nobis, Chiara Pantarelli, Antonia L Cadell, Yolande E I O'Donnell, King Ho Leong, Sophie Lynn, Fan-Suo Geng, Lujing Cui, Sabrina Yan, Joanna Achinger-Kawecka, Clare Stirzaker, Murray D Norris, Michelle Haber, Toby N Trahair, Frank Speleman, Katleen De Preter, Mark J Cowley, Ozren Bogdanovic, Paul Timpson, Thomas R Cox, Walter Kolch, Jamie I Fletcher, Dirk Fey, David R Croucher
Memory of stochastic single-cell apoptotic signaling promotes chemoresistance in neuroblastoma. Science advances 9 (9) (2023)
Ebru Boslem, Saskia Reibe, Rodrigo Carlessi, Benoit Smeuninx, Surafel Tegegne, Casey L Egan, Emma McLennan, Lauren V Terry, Max Nobis, Andre Mu, Cameron J Nowell, Neil U Horadagoda, Natalie A Mellett, Paul Timpson, Matthew Jones, Elena Denisenko, Alistair R R Forrest, Janina E E Tirnitz-Parker, Peter J Meikle, Stefan Rose-John, Michael Karin, Mark A Febbraio
Therapeutic blockade of ER stress and inflammation prevents NASH and progression to HCC. Science advances 9 (37) (2023)
Colinda L G J Scheele, David Herrmann, Erika Yamashita, Cristina Lo Celso, Craig N Jenne, Maja H Oktay, David Entenberg, Peter Friedl, Roberto Weigert, Franck L B Meijboom, Masaru Ishii, Paul Timpson, Jacco van Rheenen
Multiphoton intravital microscopy of rodents. Nature reviews. Methods primers 2 (2022)
Nicola S Meagher, Kylie L Gorringe, Matthew J Wakefield, Adelyn Bolithon, Chi Nam Ignatius Pang, Derek S Chiu, Michael S Anglesio, Kylie-Ann Mallitt, Jennifer Anne Doherty, Holly R Harris, Joellen M Schildkraut, Andrew Berchuck, Kara L Cushing-Haugen, Ksenia Chezar, Angela Chou, Adeline Tan, Jennifer Alsop, Ellen L Barlow, Matthias W Beckmann, Jessica Boros, David D L Bowtell, Alison H Brand, James D Brenton, Ian G Campbell, Dane Cheasley, Joshua G Cohen, Cezary Cybulski, Esther Elishaev, Ramona Erber, Rhonda Farrell, Anna Katharina Fischer, Zhuxuan Fu, C Blake Gilks, Anthony J Gill, Charlie Gourley, Marcel Grube, Paul R Harnett, Arndt Hartmann, Anusha Hettiaratchi, Claus K Høgdall, Tomasz Huzarski, Anna Jakubowska, Mercedes Jimenez-Linan, Catherine J Kennedy, Byoung Gie Kim, Jae-Weon Kim, Jae-Hoon Kim, Kayla Klett, Jennifer M Koziak, Tiffany Lai, Angela Laslavic, Jenny Lester, Yee Leung, Na Li, Winston Liauw, Belle W X Lim, Anna Linder, Jan A Lubiński, Sakshi Mahale, Constantina Mateoiu, Simone McInerny, Janusz Menkiszak, Parham Minoo, Suzana Mittelstadt, David L Morris, Sandra Orsulic, Sang-Yoon Park, Celeste Leigh Pearce, John V Pearson, Malcolm C Pike, Carmel M Quinn, Ganendra Raj Mohan, Jian Yu Rao, Marjorie J Riggan, Matthias Ruebner, Stuart Salfinger, Clare L Scott, Mitul Shah, Helen Steed, Colin J R Stewart, Deepak N Subramanian, Soseul Sung, Katrina Tang, Paul Timpson, Robyn L Ward, Rebekka Wiedenhoefer, Heather Thorne, Paul Andrew Cohen, Philip J Crowe, Peter Andreas Fasching, Jacek Gronwald, Nicholas J Hawkins, Estrid V S Høgdall, David G Huntsman, Paul A James, Beth Y Karlan, Linda E Kelemen, Stefan Kommoss, Gottfried E Konecny, Francesmary Modugno, Sue-Kyung Park, Annette Staebler, Karin Sundfelt, Anna H Wu, Aline Talhouk, Paul David Peter Pharoah, Lyndal Anderson, Anna De Fazio, Martin Koebel, Michael L Friedlander, Susan J Ramus
Gene expression profiling of mucinous ovarian tumors and comparison with upper and lower gastrointestinal tumors identifies markers associated with adverse outcomes. Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Kendelle J Murphy, Jessie Zhu, Michael Trpceski, Brooke A Pereira, Paul Timpson, David Herrmann
Focal adhesion kinase priming in pancreatic cancer, altering biomechanics to improve chemotherapy. Biochemical Society transactions 50 (4) (2022)
Michael Papanicolaou, Amelia L Parker, Michelle Yam, Elysse C Filipe, Sunny Z Wu, Jessica L Chitty, Kaitlin Wyllie, Emmi Tran, Ellie Mok, Audrey Nadalini, Joanna N Skhinas, Morghan C Lucas, David Herrmann, Max Nobis, Brooke A Pereira, Andrew M K Law, Lesley Castillo, Kendelle J Murphy, Anaiis Zaratzian, Jordan F Hastings, David R Croucher, Elgene Lim, Brian G Oliver, Fatima Valdes Mora, Benjamin L Parker, David Gallego Ortega, Alexander Swarbrick, Sandra O'Toole, Paul Timpson, Thomas R Cox
Temporal profiling of the breast tumour microenvironment reveals collagen XII as a driver of metastasis. Nature communications 13 (1) (2022)
Kendelle J Murphy, Daniel A Reed, Claire Vennin, James R W Conway, Max Nobis, Julia X Yin, Cecilia R Chambers, Brooke A Pereira, Victoria Lee, Elysse C Filipe, Michael Trpceski, Shona Ritchie, Morghan C Lucas, Sean C Warren, Joanna N Skhinas, Astrid Magenau, Xanthe L Metcalf, Janett Stoehr, Gretel S Major, Ashleigh Parkin, Romain Bidanel, Ruth J Lyons, Anaiis Zaratzian, Michael Tayao, Andrew Da Silva, Lea Abdulkhalek, null null, null null, Anthony J Gill, Amber L Johns, Andrew V Biankin, Jaswinder Samra, Sean M Grimmond, Angela Chou, Jacky G Goetz, Michael Susithiran Samuel, J Guy Lyons, Andrew Burgess, C Elizabeth Caldon, Lisa G Horvath, Roger J Daly, Nikolaj Gadegaard, Yingxiao Wang, Owen James Sansom, Jennifer P Morton, Thomas R Cox, Marina Pajic, David Herrmann, Paul Timpson
Intravital imaging technology guides FAK-mediated priming in pancreatic cancer precision medicine according to Merlin status. Science advances 7 (40) (2021)
Cecilia R Chambers, Shona Ritchie, Brooke A Pereira, Paul Timpson
Overcoming the senescence-associated secretory phenotype (SASP): a complex mechanism of resistance in the treatment of cancer. Molecular oncology 15 (12) (2021)
Shona Ritchie, Brooke A Pereira, Claire Vennin, Paul Timpson
Targeting genetically-tuned CAFs in pancreatic cancer via perlecan manipulation. Expert opinion on therapeutic targets 24 (3) (2020)
Monira Hoque, Yasmin A Elmaghrabi, Meryem Köse, Syed S Beevi, Jaimy Jose, Elsa Meneses-Salas, Patricia Blanco-Muñoz, James R W Conway, Alexander Swarbrick, Paul Timpson, Francesc Tebar, Carles Rentero, Carles Rentero, Thomas Grewal
Annexin A6 improves anti-migratory and anti-invasive properties of tyrosine kinase inhibitors in EGFR overexpressing human squamous epithelial cells. The FEBS journal 287 (14) (2020)
Jessica L Chitty, Joanna N Skhinas, Elysse C Filipe, Shan Wang, Carmen Rodriguez Cupello, Rhiannon D Grant, Michelle Yam, Michael Papanicolaou, Gretel Major, Anaiis Zaratzian, Andrew M Da Silva, Michael Tayao, Claire Vennin, Paul Timpson, Chris Denis Madsen, Thomas R Cox
The Mini-Organo: A rapid high-throughput 3D coculture organotypic assay for oncology screening and drug development. Cancer reports (Hoboken, N.J.) 3 (1) (2019)
Jessica L Chitty, Elysse C Filipe, Morghan C Lucas, David Herrmann, Thomas R Cox, Paul Timpson
Recent advances in understanding the complexities of metastasis. F1000Research 7 (2018)
Sarah Theresa Boyle, Jasreen Kular, Max Nobis, Andrew Ruszkiewicz, Paul Timpson, Michael Susithiran Samuel
Acute compressive stress activates RHO/ROCK-mediated cellular processes. Small GTPases 11 (5) (2018)
Max Nobis, David Herrmann, Sean C Warren, Douglas Strathdee, Thomas R Cox, Kurt I Anderson, Paul Timpson
Shedding new light on RhoA signalling as a drug target in vivo using a novel RhoA-FRET biosensor mouse. Small GTPases 11 (4) (2018)
Max Nobis, Sean C Warren, Morghan C Lucas, Kendelle J Murphy, David Herrmann, Paul Timpson
Molecular mobility and activity in an intravital imaging setting - implications for cancer progression and targeting. Journal of cell science 131 (5) (2018)
Jessica L Chitty, Elysse C Filipe, Morghan C Lucas, David Herrmann, Thomas R Cox, Paul Timpson
Recent advances in understanding the complexities of metastasis. F1000Research (2018)
Claire Vennin, Nicola Rath, Marina Pajic, Michael F Olson, Paul Timpson
Targeting ROCK activity to disrupt and prime pancreatic cancer for chemotherapy. Small GTPases 11 (1) (2017)
Adelaide I J Young, Paul Timpson, David Gallego Ortega, Christopher J Ormandy, Samantha Richelle Oakes
Myeloid cell leukemia 1 (MCL-1), an unexpected modulator of protein kinase signaling during invasion. Cell adhesion & migration 12 (6) (2017)