Bias in observational studies on the effectiveness of in hospital use of hydroxychloroquine in COVID-19.

M Mirjam HempeniusS H Sophie BotsR H H Rolf GroenwoldA Ton de BoerO H Olaf KlungelH Helga Gardarsdottir

Published in: Pharmacoepidemiology and drug safety (2023)

Overall, the quality of observational HCQ studies was heterogeneous. Synthesis of evidence of effectiveness of HCQ in COVID-19 should focus on RCTs and carefully consider the added value and quality of observational evidence. This article is protected by copyright. All rights reserved.

Keyphrases

coronavirus disease
sars cov
randomized controlled trial
systematic review
cross sectional
healthcare
quality improvement
emergency department
acute care
adverse drug