Differentiation of Human Wharton Jelly Mesenchymal Stem Cells into Germ-Like Cells; emphasis on evaluation of Germ-long non-coding RNAs.

Samira GhasemiMohammad ShafieeGordon A FernsJalil Tavakol-AfshariMohsen SaeediSara RajiNaser Mobarra

Published in: Molecular biology reports (2022)

Our study showed that BMP4 and RA are effective in inducing HWJ-MSCs differentiation into GLCs. In addition, our study for the first time showed changes in the lncRNAs expression during the differentiation of HWJ-MSCs into GLCs by using BMP4 and RA.

Keyphrases

mesenchymal stem cells
umbilical cord
long non coding rna
poor prognosis
rheumatoid arthritis
bone marrow
stem cells
cell therapy
systemic sclerosis
interstitial lung disease
bone regeneration
pluripotent stem cells