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Solid Organ Transplant Recipients Exhibit More TET2-Mutant Clonal Hematopoiesis of Indeterminate Potential Not Driven by Increased Transplantation Risk.

Alexander James SilverCaitlyn VlasschaertTaralynn M MackBrian SharberYaomin XuAlexander G BickC Wright PinsonMichael R Savona
Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
These results demonstrate that recipients of solid organ transplants display a unique pattern of clonal hematopoiesis with enrichment of TET2 driver mutations, the causes of which remain unclear and are deserving of further study.
Keyphrases
  • risk assessment
  • cell therapy
  • hematopoietic stem cell
  • human health
  • mesenchymal stem cells
  • kidney transplantation