Michael R Savona (Michael Savona)

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 62

Top Topics

Acute Myeloid Leukemia

Multiple Myeloma

Decision Making

Top Venues

medRxiv : the preprint server for health sciences

This page only lists publications with an associated author ORCID identifier.

Publications

Morgan L Shannon, Jonathan Brett Heimlich, Sydney Olson, Ariana Debevec, Zachary Copeland, Ashwin Kishtagari, Caitlyn Vlasschaert, Christina A Snider, Alexander J Silver, Donovan Brown, Travis Spaulding, Manasa Bhatta, Kelly Pugh, Shannon S Stockton, Jessica Ulloa, Yaomin Xu, Muhamed Baljevic, Javid Moslehi, Eiman Jahangir, P Brent Ferrell, David Slosky, Alexander G Bick, Michael R Savona
Clonal hematopoiesis and inflammation in the vasculature: CHIVE, a prospective, longitudinal clonal hematopoiesis cohort and biorepository. Blood advances 8 (13) (2024)
Andrew J Monteith, Haley E Ramsey, Alexander James Silver, Donovan J Brown, Dalton L Greenwood, Brianna N Smith, Ashley D Wise, Juan Liu, Sarah D Olmstead, Jackson Watke, Maria P Arrate, Agnieszka E Gorska, Londa Fuller, Jason W Locasale, Matthew C Stubbs, Jeffrey C Rathmell, Michael R Savona
Lactate Utilization Enables Metabolic Escape to Confer Resistance to BET Inhibition in Acute Myeloid Leukemia. Cancer research 84 (7) (2024)
Andrew J Monteith, Haley E Ramsey, Alexander James Silver, Donovan J Brown, Dalton L Greenwood, Brianna N Smith, Ashley D Wise, Juan Liu, Sarah D Olmstead, Jackson Watke, Maria P Arrate, Agnieszka E Gorska, Londa Fuller, Jason W Locasale, Matthew C Stubbs, Jeffrey C Rathmell, Michael R Savona
Lactate Utilization Enables Metabolic Escape to Confer Resistance to BET Inhibition in Acute Myeloid Leukemia. Cancer research 84 (7) (2024)
Maria Sirenko, Elsa Bernard, Maria Creignou, Dylan Domenico, Andrea Farina, Juan Esteban Arango Ossa, Olivier Kosmider, Robert P Hasserjian, Martin Jädersten, Ulrich Germing, Guillermo F Sanz, Arjan A van de Loosdrecht, Carmelo Gurnari, Matilde Y Follo, Felicitas R Thol, Lurdes Zamora, Andrea Pellagatti, Harold Kunal Elias, Detlef Thomas Haase, Birgitta Sander, Elisa Orna, Katharina Zoldan, Lea Naomi Eder, Wolfgang R Sperr, Renate Thalhammer, Christina Ganster, Lionel Ades, Magnus Tobiasson, Laura Palomo, Matteo Giovanni Della Porta, Kety H Huberman, Pierre Fenaux, Monika Belickova, Michael R Savona, Virginia Klimek, Fabio Pires de Souza Santos, Jacqueline Boultwood, Ioannis Kotsianidis, Valeria Santini, Francisco Solé, Uwe Platzbecker, Michael Heuser, Peter Valent, Carlo Finelli, Maria Teresa Teresa Voso, Lee-Yung Shih, Seishi Ogawa, Michaela Fontenay, Joop H Jansen, José Cervera, Benjamin L Ebert, Rafael Bejar, Peter L Greenberg, Norbert Gattermann, Luca Malcovati, Mario Cazzola, David B Beck, Eva S Hellstrom-Lindberg, Elli Papaemmanuil, Ronald Feitosa Pinheiro
Molecular and clinical presentation of UBA1-mutated myelodysplastic syndromes. Blood (2024)
Zhuoer Xie, Rami S Komrokji, Najla Al-Ali, Alexandra Regelson, Susan Geyer, Anand Ashwin Patel, Caner Saygin, Amer M Zeidan, Jan Philipp Bewersdorf, Lourdes M Mendez, Ashwin Kishtagari, Joshua F Zeidner, Catherine C Coombs, Yazan F Madanat, Stephen S Chung, Talha Badar, James M Foran, Pinkal Desai, Charlton Tsai, Elizabeth A Griffiths, Monzr M Al Malki, Idoroenyi Amanam, Catherine E Lai, H Joachim Deeg, Lionel Ades, Cecilia Arana-Yi, Afaf E G Osman, Shira Naomi Dinner, Yasmin M Abaza, Justin Taylor, Namrata S Chandhok, Deborah Soong, Andrew M Brunner, Hetty E Carraway, Abhay Singh, Chiara Elena, Jacqueline Ferrari, Anna Galli, Sara Pozzi, Eric Padron, Mirinal S Patnaik, Luca Malcovati, Michael R Savona, Aref A Al-Kali
Risk Prediction for Clonal Cytopenia: Multicenter Real-World Evidence. Blood (2024)
Jonathan Brett Heimlich, Pawan Bhat, Alyssa C Parker, Matthew T Jenkins, Caitlyn Vlasschaert, Jessica Ulloa, Joseph C Van Amburg, Chad R Potts, Sydney Olson, Alexander James Silver, Ayesha Ahmad, Brian Sharber, Donovan J Brown, Ningning Hu, Peter van Galen, Michael R Savona, Alexander G Bick, Paul Brent Ferrell
Multiomic profiling of human clonal hematopoiesis reveals genotype and cell-specific inflammatory pathway activation. Blood advances 8 (14) (2024)
Alexander James Silver, Caitlyn Vlasschaert, Taralynn M Mack, Brian Sharber, Yaomin Xu, Alexander G Bick, C Wright Pinson, Michael R Savona
Solid Organ Transplant Recipients Exhibit More TET2-Mutant Clonal Hematopoiesis of Indeterminate Potential Not Driven by Increased Transplantation Risk. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (11) (2024)
Nick Strayer, Tess Vessels, Karmel W Choi, Siwei Zhang, Yajing Li, Lide Han, Brian Sharber, Ryan S Hsi, Cosmin A Bejan, Alexander G Bick, Justin M Balko, Douglas B Johnson, Lee E Wheless, Quinn S Wells, Elizabeth J Philips, Jill M Pulley, Wesley H Self, Qingxia Chen, Tina V Hartert, Consuelo H Wilkins, Michael R Savona, Yu Shyr, Dan M Roden, Jordan W Smoller, Douglas M Ruderfer, Yaomin Xu
Interoperability of phenome-wide multimorbidity patterns: a comparative study of two large-scale EHR systems. medRxiv : the preprint server for health sciences (2024)
Nick Strayer, Tess Vessels, Karmel W Choi, Siwei Zhang, Yajing Li, Lide Han, Brian Sharber, Ryan S Hsi, Cosmin A Bejan, Alexander G Bick, Justin M Balko, Douglas B Johnson, Lee E Wheless, Quinn S Wells, Elizabeth J Philips, Jill M Pulley, Wesley H Self, Qingxia Chen, Tina V Hartert, Consuelo H Wilkins, Michael R Savona, Yu Shyr, Dan M Roden, Jordan W Smoller, Douglas M Ruderfer, Yaomin Xu
Interoperability of phenome-wide multimorbidity patterns: a comparative study of two large-scale EHR systems. medRxiv : the preprint server for health sciences (2024)
Jonathan Brett Heimlich, Pawan Bhat, Alyssa C Parker, Matthew T Jenkins, Caitlyn Vlasschaert, Jessica Ulloa, Joseph C Van Amburg, Chad R Potts, Sydney Olson, Alexander James Silver, Ayesha Ahmad, Brian Sharber, Donovan J Brown, Ningning Hu, Peter van Galen, Michael R Savona, Alexander G Bick, Paul Brent Ferrell
Multiomic profiling of human clonal hematopoiesis reveals genotype and cell-specific inflammatory pathway activation. Blood advances 8 (14) (2024)
Nick Strayer, Tess Vessels, Karmel W Choi, Siwei Zhang, Yajing Li, Lide Han, Brian Sharber, Ryan S Hsi, Cosmin A Bejan, Alexander G Bick, Justin M Balko, Douglas B Johnson, Lee E Wheless, Quinn S Wells, Elizabeth J Philips, Jill M Pulley, Wesley H Self, Qingxia Chen, Tina V Hartert, Consuelo H Wilkins, Michael R Savona, Yu Shyr, Dan M Roden, Jordan W Smoller, Douglas M Ruderfer, Yaomin Xu
Interoperability of phenome-wide multimorbidity patterns: a comparative study of two large-scale EHR systems. medRxiv : the preprint server for health sciences (2024)
Morgan L Shannon, Jonathan Brett Heimlich, Sydney Olson, Ariana Debevec, Zachary Copeland, Ashwin Kishtagari, Caitlyn Vlasschaert, Christina A Snider, Alexander J Silver, Donovan Brown, Travis Spaulding, Manasa Bhatta, Kelly Pugh, Shannon S Stockton, Jessica Ulloa, Yaomin Xu, Muhamed Baljevic, Javid Moslehi, Eiman Jahangir, P Brent Ferrell, David Slosky, Alexander G Bick, Michael R Savona
Clonal hematopoiesis and inflammation in the vasculature: CHIVE, a prospective, longitudinal clonal hematopoiesis cohort and biorepository. Blood advances 8 (13) (2024)
Elsa Bernard, Robert P Hasserjian, Peter L Greenberg, Juan Esteban Arango Ossa, Maria Creignou, Heinz Tuechler, Jesús Gutiérrez-Abril, Dylan Domenico, Juan Santiago Medina-Martinez, Max Fine Levine, Konstantinos Liosis, Noushin Farnoud, Maria Sirenko, Martin Jädersten, Ulrich Germing, Guillermo F Sanz, Arjan A Van de Loosdrecht, Yasuhito Nannya, Olivier Kosmider, Matilde Y Follo, Felicitas R Thol, Lurdes Zamora, Ronald Feitosa Pinheiro, Andrea Pellagatti, Harold Kunal Elias, Detlef Thomas Haase, Christina Ganster, Lionel Ades, Magnus Tobiasson, Laura Palomo, Matteo Giovanni Della Porta, Pierre Fenaux, Monika Belickova, Michael R Savona, Virginia Klimek, Fabio Pires de Souza Santos, Jacqueline Boultwood, Ioannis Kotsianidis, Valeria Santini, Francisco Solé, Uwe Platzbecker, Michael Heuser, Peter Valent, Carlo Finelli, Maria Teresa Teresa Voso, Lee-Yung Shih, Michaela Fontenay, Joop H Jansen, José Cervera, Norbert Gattermann, Benjamin L Ebert, Rafael Bejar, Luca Malcovati, Seishi Ogawa, Mario Cazzola, Eva S Hellstrom-Lindberg, Elli Papaemmanuil
Molecular Taxonomy of Myelodysplastic Syndromes and its Clinical Implications. Blood (2024)
Maria Sirenko, Elsa Bernard, Maria Creignou, Dylan Domenico, Andrea Farina, Juan Esteban Arango Ossa, Olivier Kosmider, Robert P Hasserjian, Martin Jädersten, Ulrich Germing, Guillermo F Sanz, Arjan A van de Loosdrecht, Carmelo Gurnari, Matilde Y Follo, Felicitas R Thol, Lurdes Zamora, Ronald Feitosa Pinheiro, Andrea Pellagatti, Harold Kunal Elias, Detlef Thomas Haase, Birgitta Sander, Elisa Orna, Katharina Zoldan, Lea Naomi Eder, Wolfgang R Sperr, Renate Thalhammer, Christina Ganster, Lionel Ades, Magnus Tobiasson, Laura Palomo, Matteo Giovanni Della Porta, Kety H Huberman, Pierre Fenaux, Monika Belickova, Michael R Savona, Virginia Klimek, Fabio Pires de Souza Santos, Jacqueline Boultwood, Ioannis Kotsianidis, Valeria Santini, Francisco Solé, Uwe Platzbecker, Michael Heuser, Peter Valent, Carlo Finelli, Maria Teresa Teresa Voso, Lee-Yung Shih, Seishi Ogawa, Michaela Fontenay, Joop H Jansen, José Cervera, Benjamin L Ebert, Rafael Bejar, Peter L Greenberg, Norbert Gattermann, Luca Malcovati, Mario Cazzola, David B Beck, Eva S Hellstrom-Lindberg, Elli Papaemmanuil
Molecular and clinical presentation of UBA1-mutated myelodysplastic syndromes. Blood (2024)
Jonathan Brett Heimlich, Pawan Bhat, Alyssa C Parker, Matthew T Jenkins, Caitlyn Vlasschaert, Jessica Ulloa, Joseph C Van Amburg, Chad R Potts, Sydney Olson, Alexander James Silver, Ayesha Ahmad, Brian Sharber, Donovan J Brown, Ningning Hu, Peter van Galen, Michael R Savona, Alexander G Bick, Paul Brent Ferrell
Multiomic profiling of human clonal hematopoiesis reveals genotype and cell-specific inflammatory pathway activation. Blood advances 8 (14) (2024)
Alexander James Silver, Donovan J Brown, Sarah D Olmstead, Jackson M Watke, Agnieszka E Gorska, Londa Tanner, Haley E Ramsey, Michael R Savona
Repair of leukemia-associated single nucleotide variants via interallelic gene conversion. bioRxiv : the preprint server for biology (2024)
Andrew J Monteith, Haley E Ramsey, Alexander James Silver, Donovan J Brown, Dalton L Greenwood, Brianna N Smith, Ashley D Wise, Juan Liu, Sarah D Olmstead, Jackson Watke, Maria P Arrate, Agnieszka E Gorska, Londa Fuller, Jason W Locasale, Matthew C Stubbs, Jeffrey C Rathmell, Michael R Savona
Lactate utilization enables metabolic escape to confer resistance to BET inhibition in acute myeloid leukemia. Cancer research (2024)
Nick Strayer, Tess Vessels, Karmel W Choi, Siwei Zhang, Yajing Li, Lide Han, Brian Sharber, Ryan S Hsi, Cosmin A Bejan, Alexander G Bick, Justin M Balko, Douglas B Johnson, Lee E Wheless, Quinn S Wells, Elizabeth J Philips, Jill M Pulley, Wesley H Self, Qingxia Chen, Tina V Hartert, Consuelo H Wilkins, Michael R Savona, Yu Shyr, Dan M Roden, Jordan W Smoller, Douglas M Ruderfer, Yaomin Xu
Interoperability of phenome-wide multimorbidity patterns: a comparative study of two large-scale EHR systems. medRxiv : the preprint server for health sciences (2024)
Alexander James Silver, Caitlyn Vlasschaert, Taralynn M Mack, Brian Sharber, Yaomin Xu, Alexander G Bick, C Wright Pinson, Michael R Savona
Solid Organ Transplant Recipients Exhibit More TET2-Mutant Clonal Hematopoiesis of Indeterminate Potential Not Driven by Increased Transplantation Risk. Clinical cancer research : an official journal of the American Association for Cancer Research 30 (11) (2024)
Andrew J Monteith, Haley E Ramsey, Alexander James Silver, Donovan J Brown, Dalton L Greenwood, Brianna N Smith, Ashley D Wise, Juan Liu, Sarah D Olmstead, Jackson Watke, Maria P Arrate, Agnieszka E Gorska, Londa Fuller, Jason W Locasale, Matthew C Stubbs, Jeffrey C Rathmell, Michael R Savona
Lactate Utilization Enables Metabolic Escape to Confer Resistance to BET Inhibition in Acute Myeloid Leukemia. Cancer research 84 (7) (2024)
Nick Strayer, Tess Vessels, Karmel W Choi, Siwei Zhang, Yajing Li, Lide Han, Brian Sharber, Ryan S Hsi, Cosmin A Bejan, Alexander G Bick, Justin M Balko, Douglas B Johnson, Lee E Wheless, Quinn S Wells, Elizabeth J Philips, Jill M Pulley, Wesley H Self, Qingxia Chen, Tina V Hartert, Consuelo H Wilkins, Michael R Savona, Yu Shyr, Dan M Roden, Jordan W Smoller, Douglas M Ruderfer, Yaomin Xu
Interoperability of phenome-wide multimorbidity patterns: a comparative study of two large-scale EHR systems. medRxiv : the preprint server for health sciences (2024)
Morgan L Shannon, Jonathan Brett Heimlich, Sydney Olson, Ariana Debevec, Zachary Copeland, Ashwin Kishtagari, Caitlyn Vlasschaert, Christina A Snider, Alexander J Silver, Donovan Brown, Travis Spaulding, Manasa Bhatta, Kelly Pugh, Shannon S Stockton, Jessica Ulloa, Yaomin Xu, Muhamed Baljevic, Javid Moslehi, Eiman Jahangir, P Brent Ferrell, David Slosky, Alexander G Bick, Michael R Savona
Clonal hematopoiesis and inflammation in the vasculature: CHIVE, a prospective, longitudinal clonal hematopoiesis cohort and biorepository. Blood advances 8 (13) (2024)
Andrew J Monteith, Haley E Ramsey, Alexander James Silver, Donovan J Brown, Dalton L Greenwood, Brianna N Smith, Ashley D Wise, Juan Liu, Sarah D Olmstead, Jackson Watke, Maria P Arrate, Agnieszka E Gorska, Londa Fuller, Jason W Locasale, Matthew C Stubbs, Jeffrey C Rathmell, Michael R Savona
Lactate Utilization Enables Metabolic Escape to Confer Resistance to BET Inhibition in Acute Myeloid Leukemia. Cancer research 84 (7) (2024)
Alexander James Silver, Caitlyn Vlasschaert, Taralynn M Mack, Brian Sharber, Yaomin Xu, Alexander G Bick, C Wright Pinson, Michael R Savona
Solid organ transplant recipients exhibit more TET2-mutant clonal hematopoiesis of indeterminate potential not driven by increased transplantation risk. Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Taralynn M Mack, Caitlyn Vlasschaert, Kelly von Beck, Alexander James Silver, Jonathan Brett Heimlich, Hannah M Poisner, Henry Robert Condon, Jessica Ulloa, Andrew L Sochacki, Travis P Spaulding, Ashwin Kishtagari, Cosmin A Bejan, Yaomin Xu, Michael R Savona, Angela Jones, Alexander G Bick
Cost-effective and scalable clonal hematopoiesis assay provides insight into clonal dynamics. medRxiv : the preprint server for health sciences (2023)
David C Florian, Natalie E Bennett, Mateusz Odziomek, Jessalyn J Baljon, Mohamed Wehbe, Alyssa R Merkel, Melissa A Fischer, Michael R Savona, Julie A Rhoades, Scott A Guelcher, John Tanner Wilson
Nanoparticle STING Agonist Reprograms the Bone Marrow to an Antitumor Phenotype and Protects Against Bone Destruction. Cancer research communications 3 (2) (2023)
Dalton L Greenwood, Haley E Ramsey, Phuong T T Nguyen, Andrew R Patterson, Kelsey Voss, Jackie E Bader, Ayaka Sugiura, Zachary A Bacigalupa, Samuel G Schaefer, Xiang Ye, Debolanle O Dahunsi, Matthew Z Madden, Kathryn E Wellen, Michael R Savona, Paul Brent Ferrell, Jeffrey C Rathmell
Acly Deficiency Enhances Myelopoiesis through Acetyl Coenzyme A and Metabolic-Epigenetic Cross-Talk. ImmunoHorizons 6 (12) (2023)
Dalton L Greenwood, Haley E Ramsey, Phuong T T Nguyen, Andrew R Patterson, Kelsey Voss, Jackie E Bader, Ayaka Sugiura, Zachary A Bacigalupa, Samuel G Schaefer, Xiang Ye, Debolanle O Dahunsi, Matthew Z Madden, Kathryn E Wellen, Michael R Savona, Paul Brent Ferrell, Jeffrey C Rathmell
Acly Deficiency Enhances Myelopoiesis through Acetyl Coenzyme A and Metabolic-Epigenetic Cross-Talk. ImmunoHorizons 6 (12) (2023)
Dalton L Greenwood, Haley E Ramsey, Phuong T T Nguyen, Andrew R Patterson, Kelsey Voss, Jackie E Bader, Ayaka Sugiura, Zachary A Bacigalupa, Samuel G Schaefer, Xiang Ye, Debolanle O Dahunsi, Matthew Z Madden, Kathryn E Wellen, Michael R Savona, Paul Brent Ferrell, Jeffrey C Rathmell
Acly Deficiency Enhances Myelopoiesis through Acetyl Coenzyme A and Metabolic-Epigenetic Cross-Talk. ImmunoHorizons 6 (12) (2023)
David C Florian, Natalie E Bennett, Mateusz Odziomek, Jessalyn J Baljon, Mohamed Wehbe, Alyssa R Merkel, Melissa A Fischer, Michael R Savona, Julie A Rhoades, Scott A Guelcher, John Tanner Wilson
Nanoparticle STING Agonist Reprograms the Bone Marrow to an Antitumor Phenotype and Protects Against Bone Destruction. Cancer research communications 3 (2) (2023)
Tamara Kay Moyo, Ashwin Kishtagari, Matthew Villaume, Brandon J McMahon, Sanjay R Mohan, Tess Stopczynski, Sheau-Chiann Chen, Run Fan, Yuankai Huo, Hyeonsoo Moon, Yucheng Tang, Cosmin A Bejan, Merrida Childress, Ingrid A Anderson, Kyle Rawling, Rhea M Simons, Ashley Moncrief, Rebekah Caza, Laura Dugger, Aunshka Collins, Channing V Dudley, Paul Brent Ferrell, Michael T Byrne, Stephen A Strickland, Gregory D Ayers, Bennett A Landman, Emily F Mason, Ruben A Mesa, Jeanne M Palmer, Laura C Michaelis, Michael R Savona
PI3K Inhibition Restores and Amplifies Response to Ruxolitinib in patients with Myelofibrosis. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Dalton L Greenwood, Haley E Ramsey, Phuong T T Nguyen, Andrew R Patterson, Kelsey Voss, Jackie E Bader, Ayaka Sugiura, Zachary A Bacigalupa, Samuel G Schaefer, Xiang Ye, Debolanle O Dahunsi, Matthew Z Madden, Kathryn E Wellen, Michael R Savona, Paul Brent Ferrell, Jeffrey C Rathmell
Acly Deficiency Enhances Myelopoiesis through Acetyl Coenzyme A and Metabolic-Epigenetic Cross-Talk. ImmunoHorizons 6 (12) (2023)
Dalton L Greenwood, Haley E Ramsey, Phuong T T Nguyen, Andrew R Patterson, Kelsey Voss, Jackie E Bader, Ayaka Sugiura, Zachary A Bacigalupa, Samuel G Schaefer, Xiang Ye, Debolanle O Dahunsi, Matthew Z Madden, Kathryn E Wellen, Michael R Savona, Paul Brent Ferrell, Jeffrey C Rathmell
Acly Deficiency Enhances Myelopoiesis through Acetyl Coenzyme A and Metabolic-Epigenetic Cross-Talk. ImmunoHorizons 6 (12) (2023)
Dalton L Greenwood, Haley E Ramsey, Phuong T T Nguyen, Andrew R Patterson, Kelsey Voss, Jackie E Bader, Ayaka Sugiura, Zachary A Bacigalupa, Samuel G Schaefer, Xiang Ye, Debolanle O Dahunsi, Matthew Z Madden, Kathryn E Wellen, Michael R Savona, Paul Brent Ferrell, Jeffrey C Rathmell
Acly Deficiency Enhances Myelopoiesis through Acetyl Coenzyme A and Metabolic-Epigenetic Cross-Talk. ImmunoHorizons 6 (12) (2023)
Siwei Zhang, Nicholas Strayer, Tess Vessels, Karmel W Choi, Geoffrey W Wang, Yajing Li, Cosmin A Bejan, Ryan S Hsi, Alexander G Bick, Digna R Velez Edwards, Michael R Savona, Elizabeth J Philips, Jill Pulley, Wesley H Self, Wilkins Consuelo Hopkins, Dan M Roden, Jordan W Smoller, Douglas M Ruderfer, Yaomin Xu
PheMIME: An Interactive Web App and Knowledge Base for Phenome-Wide, Multi-Institutional Multimorbidity Analysis. medRxiv : the preprint server for health sciences (2023)
Mirinal S Patnaik, Amer M Zeidan, Eric Padron, Uwe Platzbecker, David A Sallman, Amy E DeZern, Rafael Bejar, Mikkael A Sekeres, Justin Taylor, Richard F Little, Jan P Bewersdorf, Tae Kon Kim, Nina Kim, Christopher S Hourigan, Matteo G Dela Porta, Maximilian Stahl, David Steensma, Mina L Xu, Olatoyosi Odenike, Hetty E Carraway, Pierre Fenaux, Aziz Nazha, Rami S Komrokji, Sanam Loghavi, Zhuoer Xie, Robert P Hasserjian, Michael R Savona, John M Bennett
Differences in classification schemata for myelodysplastic/myeloproliferative overlap neoplasms. Leukemia 36 (12) (2022)
Dalton L Greenwood, Haley E Ramsey, Phuong T T Nguyen, Andrew R Patterson, Kelsey Voss, Jackie E Bader, Ayaka Sugiura, Zachary A Bacigalupa, Samuel G Schaefer, Xiang Ye, Debolanle O Dahunsi, Matthew Z Madden, Kathryn E Wellen, Michael R Savona, Paul Brent Ferrell, Jeffrey C Rathmell
Acly Deficiency Enhances Myelopoiesis through Acetyl Coenzyme A and Metabolic-Epigenetic Cross-Talk. ImmunoHorizons 6 (12) (2022)
Daniel A Arber, Attilio Orazi, Robert P Hasserjian, Michael J Borowitz, Katherine R Calvo, Hans Michael Kvasnicka, Sa A Wang, Adam Bagg, Tiziano Barbui, Susan Branford, Carlos E Bueso-Ramos, Jorge E Cortes, Paola Dal Cin, Courtney D D DiNardo, Hervé Dombret, Eric J Duncavage, Benjamin L Ebert, Elihu H Estey, Fabio Facchetti, Kathryn Foucar, Naseema Gangat, Umberto Gianelli, Lucy A Godley, Nicola Gökbuget, Jason Gotlib, Eva Hellström-Lindberg, Gabriela S Hobbs, Ronald Hoffman, Elias J Jabbour, Jean-Jacques Kiladjian, Richard A Larson, Michelle M Le Beau, Mignon L-C Loh, Bob Löwenberg, Elizabeth A Macintyre, Luca Malcovati, Charles G Mullighan, Charlotte M Niemeyer, Olatoyosi M Odenike, Seishi Ogawa, Alberto Orfao, Elli Papaemmanuil, Francesco Passamonti, Kimmo Porkka, Ching-Hon Pui, Jerald P Radich, Andreas Reiter, Maria Rozman, Martina Rudelius, Michael R Savona, Charles A Schiffer, Annette Schmitt-Graeff, Akiko Shimamura, Jorge Sierra, Wendy A Stock, Richard M Stone, Martin S Tallman, Jürgen Thiele, Hwei-Fang Tien, Alexandar Tzankov, Alessandro Maria Maria Vannucchi, Paresh Vyas, Andrew H Wei, Olga K Weinberg, Agnieszka Świątek, Mario Cazzola, Hartmut Döhner, Ayalew Tefferi
International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data. Blood 140 (11) (2022)
Sakshi Jasra, Orsi Giricz, Rachel Zeig-Owens, Kith Pradhan, David G Goldfarb, Angelica Barreto-Galvez, Alexander James Silver, Jiahao Chen, Srabani Sahu, Shanisha Gordon-Mitchell, Gaurav S Choudhary, Srinivas Aluri, Tushar D Bhagat, Aditi Shastri, Cosmin A Bejan, Shannon S Stockton, Travis P Spaulding, Victor Thiruthuvanathan, Hiroki Goto, Jeannine Gerhardt, Syed Hissam Haider, Arul Veerappan, Matthias Bartenstein, George Nwankwo, Carl Ola Landgren, Michael D Weiden, Jacqueline Lekostaj, Ryan Bender, Frederick Fletcher, Lee Greenberger, Benjamin L Ebert, Ulrich Steidl, Britta Will, Anna Nolan, Advaitha Madireddy, Michael R Savona, David J Prezant, Amit K Verma
High burden of clonal hematopoiesis in first responders exposed to the World Trade Center disaster. Nature medicine 28 (3) (2022)
Rami S Komrokji, Uwe Platzbecker, Pierre Fenaux, Amer M Zeidan, Guillermo Garcia Manero, Ghulam J Mufti, Valeria Santini, Maria Diez Campelo, Carlo Finelli, Joseph G Jurcic, Peter L Greenberg, Mikkael A Sekeres, Amy E DeZern, Michael R Savona, Jeevan K Shetty, Rodrigo Ito, George Zhang, Xianwei Ha, Jay T Backstrom, Amit Verma
Luspatercept for myelodysplastic syndromes/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis. Leukemia 36 (5) (2022)
Eric J Duncavage, Adam Bagg, Robert P Hasserjian, Courtney D D DiNardo, Lucy A Godley, Ilaria Iacobucci, Siddhartha Jaiswal, Luca Malcovati, Alessandro Maria Maria Vannucchi, Keyur Pravinchandra Patel, Daniel A Arber, Maria E Arcila, Rafael Bejar, Nancy Berliner, Michael J Borowitz, Susan Branford, Anna L Brown, Catherine A Cargo, Hartmut Döhner, Brunangelo Falini, Guillermo Garcia-Manero, Torsten Haferlach, Eva Hellström-Lindberg, Annette S Kim, Jeffery M Klco, Rami S Komrokji, Mignon Lee-Cheun Loh, Sanam Loghavi, Charles G Mullighan, Seishi Ogawa, Attilio Orazi, Elli Papaemmanuil, Andreas Reiter, David Morrall Ross, Michael R Savona, Akiko Shimamura, Radek C Skoda, Francisco Solé, Richard M Stone, Ayalew Tefferi, Matthew J Walter, David Wu, Benjamin L Ebert, Mario Cazzola
Genomic profiling for clinical decision making in myeloid neoplasms and acute leukemia. Blood 140 (21) (2022)
Tiffany E Guess, Chad R Potts, Pawan Bhat, Justin A Cartailler, Austin Brooks, Clinton Holt, Ashwini Yenamandra, Ferrin C Wheeler, Michael R Savona, Jean-Philippe Cartailler, P Brent Ferrell
Distinct Patterns of Clonal Evolution Drive Myelodysplastic Syndrome Progression to Secondary Acute Myeloid Leukemia. Blood cancer discovery 3 (4) (2022)
Andrew L Sochacki, Cosmin A Bejan, Shilin Zhao, Ameet Patel, Ashwin Kishtagari, Travis P Spaulding, Alexander James Silver, Shannon S Stockton, Kelly Pugh, Rodney Dixon Dorand, Manasa Ram Bhatta, Nicholas Strayer, Siwei Zhang, Christina A Snider, Thomas P Stricker, Aziz Nazha, Alexander G Bick, Yaomin Xu, Michael R Savona
Patient-specific comorbidities as prognostic variables for survival in myelofibrosis. Blood advances (2022)
Amer M Zeidan, Jan Philipp Bewersdorf, Rena Buckstein, Mikkael A Sekeres, David P Steensma, Uwe Platzbecker, Sanam Loghavi, Jacqueline Boultwood, Rafael Bejar, John M Bennett, Uma Borate, Andrew M Brunner, Hetty E Carraway, Jane E Churpek, Naval G Daver, Matteo Della Porta, Amy E DeZern, Fabio Efficace, Pierre Fenaux, Maria E Figueroa, Peter Greenberg, Elizabeth A Griffiths, Stephanie Halene, Robert P Hasserjian, Christopher S Hourigan, Nina Kim, Tae Kon Kim, Rami S Komrokji, Vijay Kutchroo, Alan F List, Richard F Little, Ravindra Majeti, Aziz Nazha, Stephen D Nimer, Olatoyosi Odenike, Eric Padron, Mirinal S Patnaik, Gail J Roboz, David A Sallman, Guillermo F Sanz, Maximilian Stahl, Daniel T Starczynowski, Justin Taylor, Zhuoer Xie, Mina L Xu, Michael R Savona, Andrew H Wei, Omar Abdel-Wahab, Valeria Santini
Finding consistency in classifications of myeloid neoplasms: a perspective on behalf of the International Workshop for Myelodysplastic Syndromes. Leukemia 36 (12) (2022)
Tamara K Moyo, Jason H Mendler, Raphael Itzykson, Ashwin Kishtagari, Eric Solary, Adam C Seegmiller, Aaron T Gerds, Gregory D Ayers, Amy E Dezern, Aziz Nazha, Peter Valent, Arjan A van de Loosdrecht, Francesco Onida, Lisa Pleyer, Blanca Xicoy Cirici, Raoul Tibes, Klaus Geissler, Rami S Komrokji, Jing Zhang, Ulrich Germing, David P Steensma, Daniel H Wiseman, Michael Pfeilstöecker, Chiara Elena, Nicholas C P Cross, Jean-Jacques Kiladjian, Michael Luebbert, Ruben A Mesa, Guillermo Montalban-Bravo, Guillermo F Sanz, Uwe Platzbecker, Mrinal M Patnaik, Eric Padron, Valeria Santini, Pierre Fenaux, Michael R Savona, null null
The ABNL-MARRO 001 study: a phase 1-2 study of randomly allocated active myeloid target compound combinations in MDS/MPN overlap syndromes. BMC cancer 22 (1) (2022)
Dalton L Greenwood, Haley E Ramsey, Phuong T T Nguyen, Andrew R Patterson, Kelsey Voss, Jackie E Bader, Ayaka Sugiura, Zachary A Bacigalupa, Samuel G Schaefer, Xiang Ye, Debolanle O Dahunsi, Matthew Z Madden, Kathryn E Wellen, Michael R Savona, Paul Brent Ferrell, Jeffrey C Rathmell
Acly Deficiency Enhances Myelopoiesis through Acetyl Coenzyme A and Metabolic-Epigenetic Cross-Talk. ImmunoHorizons 6 (12) (2022)
Maximilian Stahl, Omar Abdel-Wahab, Andrew H Wei, Michael R Savona, Mina L Xu, Zhuoer Xie, Justin Taylor, Daniel T Starczynowski, Guillermo F Sanz, David A Sallman, Valeria Santini, Gail J Roboz, Mirinal S Patnaik, Eric Padron, Olatoyosi Odenike, Aziz Nazha, Stephen D Nimer, Ravindra Majeti, Richard F Little, Steven D Gore, Alan F List, Vijay Kuchroo, Rami S Komrokji, Tae Kon Kim, Nina Kim, Christopher S Hourigan, Robert P Hasserjian, Stephanie Halene, Elizabeth A Griffiths, Peter L Greenberg, Maria E Figueroa, Pierre Fenaux, Fabio Efficace, Amy E DeZern, Matteo G Della Porta, Naval G Daver, Jane E Churpek, Hetty E Carraway, Andrew M Brunner, Uma Borate, John M Bennett, Rafael Bejar, Jacqueline Boultwood, Sanam Loghavi, Jan Philipp Bewersdorf, Uwe Platzbecker, David P Steensma, Mikkael A Sekeres, Rena J Buckstein, Amer M Zeidan
An agenda to advance research in MDS: A TOP 10 Priority List from the first international workshop in MDS (iwMDS). Blood advances (2022)
Nathan Radakovich, Manja Meggendorfer, Luca Malcovati, C Beau Hilton, Mikkael A Sekeres, Jacob Shreve, Yazan Rouphail, Wencke Walter, Stephan Hutter, Anna Galli, Sara Pozzi, Chiara Elena, Eric Padron, Michael R Savona, Aaron T Gerds, Sudipto Mukherjee, Yasunobu Nagata, Rami S Komrokji, Babal Kant Jha, Claudia Haferlach, Jaroslaw P Maciejewski, Torsten Haferlach, Aziz Nazha
A geno-clinical decision model for the diagnosis of myelodysplastic syndromes. Blood advances 5 (21) (2021)
Alexander James Silver, Alexander G Bick, Michael R Savona
Germline risk of clonal haematopoiesis. Nature reviews. Genetics 22 (9) (2021)
Haley E Ramsey, Dalton L Greenwood, Susu Zhang, Merrida Childress, Maria P Arrate, Agnieszka E Gorska, Londa Fuller, Yue Zhao, Kristy Stengel, Melissa A Fischer, Matthew C Stubbs, Phillip C C Liu, Kelli Boyd, Jeffrey C Rathmell, Scott W Hiebert, Michael R Savona
BET Inhibition Enhances the Antileukemic Activity of Low-dose Venetoclax in Acute Myeloid Leukemia. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (2) (2020)
Shanshan Pei, Daniel A Pollyea, Annika Gustafson, Brett M Stevens, Mohammad Minhajuddin, Rui Fu, Kent A Riemondy, Austin E Gillen, Ryan M Sheridan, Jihye Kim, James C Costello, Maria L Amaya, Anagha Inguva, Amanda C Winters, Haobin Ye, Anna Krug, Courtney L Jones, Biniam Adane, Nabilah Khan, Jessica Ponder, Jeffrey Schowinsky, Diana Abbott, Andrew Hammes, Jason R Myers, John M Ashton, Travis Nemkov, Angelo D'Alessandro, Jonathan A Gutman, Haley E Ramsey, Michael R Savona, Clayton A Smith, Craig T Jordan
Monocytic Subclones Confer Resistance to Venetoclax-Based Therapy in Patients with Acute Myeloid Leukemia. Cancer discovery 10 (4) (2020)
Elsa Bernard, Yasuhito Nannya, Robert P Hasserjian, Sean M Devlin, Heinz Tuechler, Juan S Medina-Martinez, Tetsuichi Yoshizato, Yusuke Shiozawa, Ryunosuke Saiki, Luca Malcovati, Max Fine Levine, Juan E Arango, Yangyu Zhou, Francesc Solé, Catherine A Cargo, Detlef Haase, Maria Creignou, Ulrich Germing, Yanming Zhang, Gunes Gundem, Araxe Sarian, Arjan A van de Loosdrecht, Martin Jädersten, Magnus Tobiasson, Olivier Kosmider, Matilde Y Follo, Felicitas Thol, Ronald F Pinheiro, Valeria Santini, Ioannis Kotsianidis, Jacqueline Boultwood, Fabio P S Santos, Julie Schanz, Senji Kasahara, Takayuki Ishikawa, Hisashi Tsurumi, Akifumi Takaori-Kondo, Toru Kiguchi, Chantana Polprasert, John M Bennett, Virginia M Klimek, Michael R Savona, Monika Belickova, Christina Ganster, Laura Palomo, Guillermo F Sanz, Lionel Ades, Matteo Giovanni Della Porta, Harold K Elias, Alexandra G Smith, Yesenia Werner, Minal Patel, Agnès Viale, Katelynd Vanness, Donna S Neuberg, Kristen E Stevenson, Kamal Menghrajani, Kelly L Bolton, Pierre Fenaux, Andrea Pellagatti, Uwe Platzbecker, Michael Heuser, Peter Valent, Shigeru Chiba, Yasushi Miyazaki, Carlo Finelli, Maria Teresa Teresa Voso, Lee-Yung Shih, Michaela Fontenay, Joop H Jansen, José Cervera, Yoshiko Atsuta, Norbert Gattermann, Benjamin L Ebert, Rafael Bejar, Peter L Greenberg, Mario Cazzola, Eva Hellström-Lindberg, Seishi Ogawa, Elli Papaemmanuil
Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes. Nature medicine 26 (10) (2020)
Daniel A Pollyea, Tracy I George, Mehrdad Abedi, Rafael Bejar, Christopher R Cogle, Kathryn Foucar, Guillermo Garcia-Manero, David L Grinblatt, Rami S Komrokji, Jaroslaw P Maciejewski, Dennis A Revicki, Gail J Roboz, Michael R Savona, Bart L Scott, Mikkael A Sekeres, Michael A Thompson, Sandra E Kurtin, Chrystal U Louis, Melissa Nifenecker, E Dawn Flick, Arlene S Swern, Pavel Kiselev, David P Steensma, Harry P Erba
Diagnostic and molecular testing patterns in patients with newly diagnosed acute myeloid leukemia in the Connect ® MDS/AML Disease Registry. EJHaem 1 (1) (2020)
Detlef Haase, Kristen E Stevenson, Donna S Neuberg, Jaroslaw P Maciejewski, Aziz Nazha, Mikkael A Sekeres, Benjamin L Ebert, Guillermo Garcia-Manero, Claudia Haferlach, Torsten Haferlach, Wolfgang Kern, Seishi Ogawa, Yasunobu Nagata, Kenichi Yoshida, Timothy A Graubert, Matthew J Walter, Alan F List, Rami S Komrokji, Eric Padron, David Sallman, Elli Papaemmanuil, Peter J Campbell, Michael R Savona, Adam Seegmiller, Lionel Adès, Pierre Fenaux, Lee-Yung Shih, David Bowen, Michael J Groves, Sudhir Tauro, Michaela Fontenay, Olivier Kosmider, Michal Bar-Natan, David Steensma, Richard Stone, Michael Heuser, Felicitas Thol, Mario Cazzola, Luca Malcovati, Aly Karsan, Christina Ganster, Eva Hellström-Lindberg, Jacqueline Boultwood, Andrea Pellagatti, Valeria Santini, Lynn Quek, Paresh Vyas, Heinz Tüchler, Peter L Greenberg, Rafael Bejar, null null
TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups. Leukemia 33 (7) (2019)
Travis P Spaulding, Shannon S Stockton, Michael R Savona
The evolving role of next generation sequencing in myelodysplastic syndromes. British journal of haematology 188 (2) (2019)
Michael R Savona, Jeffrey C Rathmell
Mitochondrial Homeostasis in AML and Gasping for Response in Resistance to BCL2 Blockade. Cancer discovery 9 (7) (2019)
Irene M Ghobrial, Ravi Vij, David Siegel, Ashraf Badros, Jonathan Kaufman, Noopur Raje, Andrzej Jakubowiak, Michael R Savona, Mihaela Obreja, Jesus G Berdeja
A Phase Ib/II Study of Oprozomib in Patients with Advanced Multiple Myeloma and Waldenström Macroglobulinemia. Clinical cancer research : an official journal of the American Association for Cancer Research 25 (16) (2019)
Ronan T Swords, Steven Coutre, Michael B Maris, Joshua F Zeidner, James M Foran, Jose Cruz, Harry P Erba, Jesus G Berdeja, Wayne Tam, Saran Vardhanabhuti, Lwona Dobler, Hélène M Faessel, Ajeeta B Dash, Farhad Sedarati, Douglas V Faller, Michael R Savona
Pevonedistat, a first-in-class NEDD8-activating enzyme inhibitor, combined with azacitidine in patients with AML. Blood 131 (13) (2018)
Haley E Ramsey, Melissa A Fischer, Taekyu Lee, Agnieszka E Gorska, Maria Pia Arrate, Londa Fuller, Kelli L Boyd, Stephen A Strickland, John Sensintaffar, Leah J Hogdal, Gregory D Ayers, Edward T Olejniczak, Stephen W Fesik, Michael R Savona
A Novel MCL1 Inhibitor Combined with Venetoclax Rescues Venetoclax-Resistant Acute Myelogenous Leukemia. Cancer discovery 8 (12) (2018)
Michael R Savona, Kathryn Kolibaba, Paul Conkling, Edwin C Kingsley, Carlos Becerra, John C Morris, Robert M Rifkin, Eric Laille, Amy Kellerman, Stacey M Ukrainskyj, Qian Dong, Barry S Skikne
Extended dosing with CC-486 (oral azacitidine) in patients with myeloid malignancies. American journal of hematology 93 (10) (2018)
Christine Chen, David Siegel, Martin Gutierrez, Meagan Jacoby, Craig C Hofmeister, Nashat Gabrail, Rachid C Baz, Morten Mau-Sorensen, Jesus G Berdeja, Michael R Savona, Lynn Savoie, Suzanne Trudel, Nuchanan Areethamsirikul, T J Unger, Tami Rashal, Tim Hanke, Michael Kauffman, Sharon Shacham, Donna Reece
Safety and efficacy of selinexor in relapsed or refractory multiple myeloma and Waldenstrom macroglobulinemia. Blood 131 (8) (2017)
Ramiro Garzon, Michael R Savona, Rachid C Baz, Michael Andreeff, Nashat Gabrail, Martin Gutierrez, Lynn Savoie, Paul Morten Mau-Sorensen, Nina Wagner-Johnston, Karen Yee, Thaddeus J Unger, Jean-Richard Saint-Martin, Robert Carlson, Tami Rashal, Trinayan Kashyap, Boris Klebanov, Sharon Shacham, Michael Kauffman, Richard Stone
A phase 1 clinical trial of single-agent selinexor in acute myeloid leukemia. Blood 129 (24) (2017)
Michael R Savona, Luca Malcovati, Rami Komrokji, Ramon V Tiu, Tariq I Mughal, Attilio Orazi, Jean-Jacques Kiladjian, Eric Padron, Eric Solary, Raoul Tibes, Raphael Itzykson, Mario Cazzola, Ruben Mesa, Jaroslaw Maciejewski, Pierre Fenaux, Guillermo Garcia-Manero, Aaron Gerds, Guillermo Sanz, Charlotte M Niemeyer, Francisco Cervantes, Ulrich Germing, Nicholas C P Cross, Alan F List, null null
An international consortium proposal of uniform response criteria for myelodysplastic/myeloproliferative neoplasms (MDS/MPN) in adults. Blood 125 (12) (2015)